Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2379c

Experiment: D,L-Malic Acid 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2378c and Rv2379c overlap by 4 nucleotidesRv2379c and Rv2380c overlap by 19 nucleotides Rv2378c: Rv2378c - Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase), at 2,656,408 to 2,657,703 Rv2378c Rv2379c: Rv2379c - Peptide synthetase MbtF (peptide synthase), at 2,657,700 to 2,662,085 Rv2379c Rv2380c: Rv2380c - Peptide synthetase MbtE (peptide synthase), at 2,662,067 to 2,667,115 Rv2380c Position (kb) 2657 2658 2659 2660 2661 2662 2663Strain fitness (log2 ratio) -1 0 1 2at 2657.006 kb on - strand, within Rv2378cat 2657.338 kb on + strand, within Rv2378cat 2657.338 kb on + strand, within Rv2378cat 2657.343 kb on - strand, within Rv2378cat 2657.436 kb on - strand, within Rv2378cat 2657.710 kb on - strandat 2657.898 kb on + strandat 2657.951 kb on - strandat 2658.095 kb on - strandat 2658.331 kb on - strand, within Rv2379cat 2659.681 kb on + strand, within Rv2379cat 2659.832 kb on - strand, within Rv2379cat 2659.832 kb on - strand, within Rv2379cat 2661.010 kb on - strand, within Rv2379cat 2661.103 kb on - strand, within Rv2379cat 2661.103 kb on - strand, within Rv2379cat 2661.799 kb on - strandat 2661.832 kb on - strandat 2662.248 kb on - strandat 2662.643 kb on - strand, within Rv2380cat 2662.662 kb on + strand, within Rv2380cat 2662.827 kb on + strand, within Rv2380cat 2662.828 kb on - strand, within Rv2380cat 2662.828 kb on - strand, within Rv2380c

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Per-strain Table

Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C)
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2,657,006 - Rv2378c 0.46 +2.3
2,657,338 + Rv2378c 0.72 +0.1
2,657,338 + Rv2378c 0.72 +0.7
2,657,343 - Rv2378c 0.72 +0.8
2,657,436 - Rv2378c 0.79 -0.0
2,657,710 - -0.5
2,657,898 + +1.9
2,657,951 - -0.1
2,658,095 - -0.4
2,658,331 - Rv2379c 0.14 -0.1
2,659,681 + Rv2379c 0.45 -0.8
2,659,832 - Rv2379c 0.49 -0.3
2,659,832 - Rv2379c 0.49 +2.3
2,661,010 - Rv2379c 0.75 -1.3
2,661,103 - Rv2379c 0.78 -0.3
2,661,103 - Rv2379c 0.78 -0.3
2,661,799 - +0.7
2,661,832 - +1.1
2,662,248 - -0.5
2,662,643 - Rv2380c 0.11 +0.6
2,662,662 + Rv2380c 0.12 +0.3
2,662,827 + Rv2380c 0.15 +0.3
2,662,828 - Rv2380c 0.15 +0.1
2,662,828 - Rv2380c 0.15 +0.7

Or see this region's nucleotide sequence