Experiment: D,L-Malic Acid 10 mM (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0957 and Rv0958 are separated by 106 nucleotides Rv0958 and Rv0959 overlap by 8 nucleotides
Rv0957: Rv0957 - Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC), at 1,068,205 to 1,069,776
Rv0957
Rv0958: Rv0958 - Possible magnesium chelatase, at 1,069,883 to 1,071,262
Rv0958
Rv0959: Rv0959 - Conserved hypothetical protein, at 1,071,255 to 1,073,273
Rv0959
Position (kb)
1069
1070
1071
1072 Strain fitness (log2 ratio)
-1
0
1
2 at 1069.869 kb on - strand at 1069.894 kb on + strand at 1069.894 kb on + strand at 1070.192 kb on + strand, within Rv0958 at 1070.193 kb on - strand, within Rv0958 at 1070.248 kb on - strand, within Rv0958 at 1070.248 kb on - strand, within Rv0958 at 1070.279 kb on + strand, within Rv0958 at 1070.570 kb on + strand, within Rv0958 at 1070.570 kb on + strand, within Rv0958 at 1070.708 kb on + strand, within Rv0958 at 1071.206 kb on + strand at 1071.207 kb on - strand at 1071.260 kb on + strand at 1071.328 kb on + strand at 1071.328 kb on + strand at 1071.329 kb on - strand at 1071.333 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C) remove 1,069,869 - +0.7 1,069,894 + +0.1 1,069,894 + -0.4 1,070,192 + Rv0958 0.22 -0.0 1,070,193 - Rv0958 0.22 -0.3 1,070,248 - Rv0958 0.26 +0.1 1,070,248 - Rv0958 0.26 +0.4 1,070,279 + Rv0958 0.29 -0.5 1,070,570 + Rv0958 0.50 +0.1 1,070,570 + Rv0958 0.50 +0.2 1,070,708 + Rv0958 0.60 +2.5 1,071,206 + -0.7 1,071,207 - -0.7 1,071,260 + +0.5 1,071,328 + +0.4 1,071,328 + +0.3 1,071,329 - -0.1 1,071,333 + -0.5
Or see this region's nucleotide sequence