Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3865

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3864 and Rv3865 are separated by 87 nucleotidesRv3865 and Rv3866 are separated by 2 nucleotidesRv3866 and Rv3867 are separated by 38 nucleotides Rv3864: Rv3864 - ESX-1 secretion-associated protein EspE, at 4,340,270 to 4,341,478 Rv3864 Rv3865: Rv3865 - ESX-1 secretion-associated protein EspF, at 4,341,566 to 4,341,877 Rv3865 Rv3866: Rv3866 - ESX-1 secretion-associated protein EspG1, at 4,341,880 to 4,342,731 Rv3866 Rv3867: Rv3867 - ESX-1 secretion-associated protein EspH, at 4,342,770 to 4,343,321 Rv3867 Position (kb) 4341 4342Strain fitness (log2 ratio) -2 -1 0 1at 4340.735 kb on - strand, within Rv3864at 4341.542 kb on + strandat 4341.549 kb on - strandat 4341.641 kb on - strand, within Rv3865at 4341.691 kb on + strand, within Rv3865at 4341.692 kb on - strand, within Rv3865at 4341.800 kb on - strand, within Rv3865at 4341.800 kb on - strand, within Rv3865at 4341.941 kb on + strandat 4341.942 kb on - strandat 4342.380 kb on - strand, within Rv3866at 4342.414 kb on + strand, within Rv3866at 4342.414 kb on + strand, within Rv3866at 4342.414 kb on + strand, within Rv3866at 4342.415 kb on - strand, within Rv3866at 4342.415 kb on - strand, within Rv3866at 4342.661 kb on + strandat 4342.662 kb on - strandat 4342.662 kb on - strandat 4342.689 kb on - strandat 4342.868 kb on - strand, within Rv3867at 4342.875 kb on + strand, within Rv3867at 4342.876 kb on - strand, within Rv3867at 4342.876 kb on - strand, within Rv3867at 4342.876 kb on - strand, within Rv3867at 4342.876 kb on - strand, within Rv3867

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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4,340,735 - Rv3864 0.38 -0.3
4,341,542 + +0.6
4,341,549 - +0.5
4,341,641 - Rv3865 0.24 -0.5
4,341,691 + Rv3865 0.40 -1.5
4,341,692 - Rv3865 0.40 -0.6
4,341,800 - Rv3865 0.75 +1.2
4,341,800 - Rv3865 0.75 -1.3
4,341,941 + +0.4
4,341,942 - -0.8
4,342,380 - Rv3866 0.59 -0.1
4,342,414 + Rv3866 0.63 -1.2
4,342,414 + Rv3866 0.63 -2.3
4,342,414 + Rv3866 0.63 +1.7
4,342,415 - Rv3866 0.63 +0.5
4,342,415 - Rv3866 0.63 -0.3
4,342,661 + -1.2
4,342,662 - -0.5
4,342,662 - -1.5
4,342,689 - -1.8
4,342,868 - Rv3867 0.18 -0.9
4,342,875 + Rv3867 0.19 -0.3
4,342,876 - Rv3867 0.19 -0.2
4,342,876 - Rv3867 0.19 -0.9
4,342,876 - Rv3867 0.19 -0.6
4,342,876 - Rv3867 0.19 -0.3

Or see this region's nucleotide sequence