Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3819

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3818 and Rv3819 overlap by 4 nucleotidesRv3819 and Rv3820c are separated by 87 nucleotides Rv3818: Rv3818 - Unknown protein, at 4,282,449 to 4,283,999 Rv3818 Rv3819: Rv3819 - Unknown protein, at 4,283,996 to 4,284,331 Rv3819 Rv3820c: Rv3820c - Possible conserved polyketide synthase associated protein PapA2, at 4,284,419 to 4,285,825 Rv3820c Position (kb) 4283 4284 4285Strain fitness (log2 ratio) -2 -1 0 1 2at 4283.005 kb on - strand, within Rv3818at 4283.080 kb on - strand, within Rv3818at 4283.137 kb on + strand, within Rv3818at 4283.138 kb on - strand, within Rv3818at 4283.186 kb on + strand, within Rv3818at 4283.736 kb on + strand, within Rv3818at 4284.024 kb on + strandat 4284.155 kb on - strand, within Rv3819at 4284.390 kb on + strandat 4284.433 kb on + strandat 4284.433 kb on + strandat 4284.434 kb on - strandat 4284.468 kb on + strandat 4284.737 kb on + strand, within Rv3820cat 4284.892 kb on + strand, within Rv3820cat 4284.892 kb on + strand, within Rv3820cat 4284.892 kb on + strand, within Rv3820cat 4284.892 kb on + strand, within Rv3820cat 4284.893 kb on - strand, within Rv3820cat 4284.893 kb on - strand, within Rv3820cat 4284.898 kb on + strand, within Rv3820cat 4284.899 kb on - strand, within Rv3820cat 4284.912 kb on - strand, within Rv3820cat 4284.982 kb on + strand, within Rv3820cat 4284.983 kb on - strand, within Rv3820cat 4285.055 kb on - strand, within Rv3820cat 4285.082 kb on + strand, within Rv3820cat 4285.082 kb on + strand, within Rv3820cat 4285.083 kb on - strand, within Rv3820cat 4285.194 kb on + strand, within Rv3820cat 4285.194 kb on + strand, within Rv3820cat 4285.272 kb on + strand, within Rv3820cat 4285.273 kb on - strand, within Rv3820cat 4285.273 kb on - strand, within Rv3820cat 4285.279 kb on + strand, within Rv3820cat 4285.280 kb on - strand, within Rv3820cat 4285.280 kb on - strand, within Rv3820c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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4,283,005 - Rv3818 0.36 -0.1
4,283,080 - Rv3818 0.41 -0.3
4,283,137 + Rv3818 0.44 +1.9
4,283,138 - Rv3818 0.44 +1.4
4,283,186 + Rv3818 0.48 -0.7
4,283,736 + Rv3818 0.83 +0.8
4,284,024 + +1.5
4,284,155 - Rv3819 0.47 -1.2
4,284,390 + +0.9
4,284,433 + +1.3
4,284,433 + -0.7
4,284,434 - -2.5
4,284,468 + +1.1
4,284,737 + Rv3820c 0.23 +0.3
4,284,892 + Rv3820c 0.34 +0.6
4,284,892 + Rv3820c 0.34 +0.3
4,284,892 + Rv3820c 0.34 -0.4
4,284,892 + Rv3820c 0.34 -0.1
4,284,893 - Rv3820c 0.34 +0.8
4,284,893 - Rv3820c 0.34 +0.4
4,284,898 + Rv3820c 0.34 -1.1
4,284,899 - Rv3820c 0.34 +0.6
4,284,912 - Rv3820c 0.35 +0.4
4,284,982 + Rv3820c 0.40 +0.4
4,284,983 - Rv3820c 0.40 +0.5
4,285,055 - Rv3820c 0.45 +0.4
4,285,082 + Rv3820c 0.47 +1.9
4,285,082 + Rv3820c 0.47 +0.9
4,285,083 - Rv3820c 0.47 +0.8
4,285,194 + Rv3820c 0.55 +0.3
4,285,194 + Rv3820c 0.55 +0.9
4,285,272 + Rv3820c 0.61 +0.3
4,285,273 - Rv3820c 0.61 -0.3
4,285,273 - Rv3820c 0.61 -0.2
4,285,279 + Rv3820c 0.61 -0.5
4,285,280 - Rv3820c 0.61 -1.1
4,285,280 - Rv3820c 0.61 +0.4

Or see this region's nucleotide sequence