Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3766

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3765c and Rv3766 are separated by 508 nucleotidesRv3766 and Rv3767c are separated by 13 nucleotides Rv3765c: Rv3765c - Probable two component transcriptional regulatory protein TcrX, at 4,211,080 to 4,211,784 Rv3765c Rv3766: Rv3766 - Hypothetical protein, at 4,212,293 to 4,212,982 Rv3766 Rv3767c: Rv3767c - Possible S-adenosylmethionine-dependent methyltransferase, at 4,212,996 to 4,213,940 Rv3767c Position (kb) 4212 4213Strain fitness (log2 ratio) -2 -1 0 1 2 3at 4211.417 kb on - strand, within Rv3765cat 4211.452 kb on - strand, within Rv3765cat 4211.468 kb on + strand, within Rv3765cat 4211.468 kb on + strand, within Rv3765cat 4211.468 kb on + strand, within Rv3765cat 4211.468 kb on + strand, within Rv3765cat 4211.498 kb on - strand, within Rv3765cat 4211.499 kb on + strand, within Rv3765cat 4211.499 kb on + strand, within Rv3765cat 4211.533 kb on + strand, within Rv3765cat 4211.533 kb on + strand, within Rv3765cat 4211.830 kb on + strandat 4211.866 kb on + strandat 4211.867 kb on - strandat 4211.867 kb on - strandat 4211.934 kb on - strandat 4211.963 kb on - strandat 4212.116 kb on - strandat 4212.258 kb on - strandat 4212.339 kb on - strandat 4212.542 kb on + strand, within Rv3766at 4212.615 kb on - strand, within Rv3766at 4212.677 kb on - strand, within Rv3766at 4212.741 kb on + strand, within Rv3766at 4212.849 kb on + strand, within Rv3766at 4212.849 kb on + strand, within Rv3766at 4213.188 kb on + strand, within Rv3767cat 4213.332 kb on - strand, within Rv3767cat 4213.332 kb on - strand, within Rv3767cat 4213.555 kb on + strand, within Rv3767cat 4213.623 kb on + strand, within Rv3767cat 4213.661 kb on - strand, within Rv3767cat 4213.771 kb on + strand, within Rv3767cat 4213.771 kb on + strand, within Rv3767cat 4213.772 kb on - strand, within Rv3767cat 4213.772 kb on - strand, within Rv3767cat 4213.782 kb on + strand, within Rv3767cat 4213.907 kb on + strandat 4213.944 kb on + strandat 4213.982 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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4,211,417 - Rv3765c 0.48 -0.5
4,211,452 - Rv3765c 0.53 -0.3
4,211,468 + Rv3765c 0.55 -0.4
4,211,468 + Rv3765c 0.55 -0.3
4,211,468 + Rv3765c 0.55 +0.2
4,211,468 + Rv3765c 0.55 -0.4
4,211,498 - Rv3765c 0.59 +0.4
4,211,499 + Rv3765c 0.59 -0.8
4,211,499 + Rv3765c 0.59 -0.3
4,211,533 + Rv3765c 0.64 -0.9
4,211,533 + Rv3765c 0.64 -0.4
4,211,830 + +1.4
4,211,866 + -0.5
4,211,867 - -0.8
4,211,867 - +0.4
4,211,934 - -0.5
4,211,963 - -0.3
4,212,116 - +0.5
4,212,258 - -0.6
4,212,339 - -1.8
4,212,542 + Rv3766 0.36 -0.9
4,212,615 - Rv3766 0.47 -0.7
4,212,677 - Rv3766 0.56 -0.6
4,212,741 + Rv3766 0.65 +2.9
4,212,849 + Rv3766 0.81 -0.6
4,212,849 + Rv3766 0.81 -1.1
4,213,188 + Rv3767c 0.20 -0.2
4,213,332 - Rv3767c 0.36 +0.5
4,213,332 - Rv3767c 0.36 -0.8
4,213,555 + Rv3767c 0.59 +0.0
4,213,623 + Rv3767c 0.66 -0.9
4,213,661 - Rv3767c 0.70 +0.2
4,213,771 + Rv3767c 0.82 -0.3
4,213,771 + Rv3767c 0.82 -0.2
4,213,772 - Rv3767c 0.82 -0.5
4,213,772 - Rv3767c 0.82 -0.9
4,213,782 + Rv3767c 0.83 -0.4
4,213,907 + +0.0
4,213,944 + +1.9
4,213,982 + -2.0

Or see this region's nucleotide sequence