Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3478

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3476c and Rv3477 are separated by 372 nucleotidesRv3477 and Rv3478 are separated by 36 nucleotidesRv3478 and Rv3479 are separated by 212 nucleotides Rv3476c: Rv3476c - Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter), at 3,892,371 to 3,893,720 Rv3476c Rv3477: Rv3477 - PE family protein PE31, at 3,894,093 to 3,894,389 Rv3477 Rv3478: Rv3478 - PE family protein PPE60, at 3,894,426 to 3,895,607 Rv3478 Rv3479: Rv3479 - Possible transmembrane protein, at 3,895,820 to 3,898,885 Rv3479 Position (kb) 3894 3895 3896Strain fitness (log2 ratio) -2 -1 0 1at 3893.513 kb on + strand, within Rv3476cat 3893.514 kb on - strand, within Rv3476cat 3893.536 kb on + strand, within Rv3476cat 3893.585 kb on - strand, within Rv3476cat 3893.588 kb on + strandat 3893.608 kb on + strandat 3893.609 kb on - strandat 3893.617 kb on + strandat 3893.617 kb on + strandat 3894.273 kb on + strand, within Rv3477at 3894.348 kb on + strand, within Rv3477at 3894.846 kb on + strand, within Rv3478at 3894.847 kb on - strand, within Rv3478at 3894.847 kb on - strand, within Rv3478at 3894.883 kb on - strand, within Rv3478at 3895.082 kb on - strand, within Rv3478at 3895.232 kb on - strand, within Rv3478at 3895.940 kb on + strandat 3895.951 kb on - strandat 3895.951 kb on - strandat 3895.951 kb on - strandat 3896.147 kb on + strand, within Rv3479at 3896.163 kb on + strand, within Rv3479at 3896.261 kb on + strand, within Rv3479at 3896.262 kb on - strand, within Rv3479at 3896.406 kb on + strand, within Rv3479

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,893,513 + Rv3476c 0.85 -0.7
3,893,514 - Rv3476c 0.85 -0.7
3,893,536 + Rv3476c 0.86 +0.4
3,893,585 - Rv3476c 0.90 -0.1
3,893,588 + -1.1
3,893,608 + +0.3
3,893,609 - +1.5
3,893,617 + -2.0
3,893,617 + -0.1
3,894,273 + Rv3477 0.61 -1.4
3,894,348 + Rv3477 0.86 -0.6
3,894,846 + Rv3478 0.36 +0.5
3,894,847 - Rv3478 0.36 -0.2
3,894,847 - Rv3478 0.36 -0.9
3,894,883 - Rv3478 0.39 -0.8
3,895,082 - Rv3478 0.55 -0.4
3,895,232 - Rv3478 0.68 -2.6
3,895,940 + -1.3
3,895,951 - +0.2
3,895,951 - +0.0
3,895,951 - -0.3
3,896,147 + Rv3479 0.11 +0.4
3,896,163 + Rv3479 0.11 -0.9
3,896,261 + Rv3479 0.14 -0.5
3,896,262 - Rv3479 0.14 -0.1
3,896,406 + Rv3479 0.19 -0.2

Or see this region's nucleotide sequence