Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3311

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3310 and Rv3311 are separated by 23 nucleotidesRv3311 and Rv3312c are separated by 20 nucleotides Rv3310: Rv3310 - Acid phosphatase (acid phosphomonoesterase) (phosphomonoesterase) (glycerophosphatase), at 3,697,198 to 3,698,097 Rv3310 Rv3311: Rv3311 - Conserved protein, at 3,698,121 to 3,699,383 Rv3311 Rv3312c: Rv3312c - Conserved hypothetical protein, at 3,699,404 to 3,700,330 Rv3312c Position (kb) 3698 3699 3700Strain fitness (log2 ratio) -1 0 1 2at 3697.187 kb on - strandat 3697.187 kb on - strandat 3697.188 kb on + strandat 3697.189 kb on - strandat 3697.189 kb on - strandat 3697.241 kb on + strandat 3697.597 kb on + strand, within Rv3310at 3697.663 kb on + strand, within Rv3310at 3697.698 kb on + strand, within Rv3310at 3697.754 kb on - strand, within Rv3310at 3697.861 kb on + strand, within Rv3310at 3697.862 kb on - strand, within Rv3310at 3697.982 kb on - strand, within Rv3310at 3698.032 kb on + strandat 3698.032 kb on + strandat 3698.076 kb on - strandat 3698.096 kb on - strandat 3698.137 kb on + strandat 3698.137 kb on + strandat 3698.172 kb on + strandat 3698.247 kb on + strandat 3698.247 kb on + strandat 3698.824 kb on + strand, within Rv3311at 3699.105 kb on + strand, within Rv3311at 3699.105 kb on + strand, within Rv3311at 3699.106 kb on - strand, within Rv3311at 3699.273 kb on + strandat 3699.273 kb on + strandat 3699.273 kb on + strandat 3699.274 kb on - strandat 3699.274 kb on - strandat 3699.405 kb on + strandat 3699.532 kb on - strand, within Rv3312cat 3699.580 kb on + strand, within Rv3312cat 3699.580 kb on + strand, within Rv3312cat 3699.586 kb on + strand, within Rv3312cat 3699.586 kb on + strand, within Rv3312cat 3699.645 kb on + strand, within Rv3312cat 3699.645 kb on + strand, within Rv3312cat 3699.645 kb on + strand, within Rv3312cat 3699.646 kb on - strand, within Rv3312cat 3699.646 kb on - strand, within Rv3312cat 3699.646 kb on - strand, within Rv3312cat 3699.766 kb on + strand, within Rv3312cat 3699.766 kb on + strand, within Rv3312cat 3699.787 kb on - strand, within Rv3312cat 3699.858 kb on + strand, within Rv3312cat 3699.859 kb on - strand, within Rv3312cat 3700.104 kb on + strand, within Rv3312cat 3700.125 kb on - strand, within Rv3312cat 3700.203 kb on + strand, within Rv3312cat 3700.204 kb on - strand, within Rv3312cat 3700.243 kb on - strandat 3700.348 kb on + strandat 3700.349 kb on - strandat 3700.349 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,697,187 - +0.3
3,697,187 - -0.7
3,697,188 + -0.7
3,697,189 - -1.3
3,697,189 - -0.6
3,697,241 + -0.6
3,697,597 + Rv3310 0.44 -0.5
3,697,663 + Rv3310 0.52 +1.2
3,697,698 + Rv3310 0.56 -0.7
3,697,754 - Rv3310 0.62 +0.4
3,697,861 + Rv3310 0.74 +1.4
3,697,862 - Rv3310 0.74 +1.9
3,697,982 - Rv3310 0.87 -0.4
3,698,032 + -0.8
3,698,032 + -0.2
3,698,076 - -0.9
3,698,096 - -0.5
3,698,137 + -0.1
3,698,137 + +0.3
3,698,172 + -1.6
3,698,247 + +0.8
3,698,247 + -1.4
3,698,824 + Rv3311 0.56 -0.0
3,699,105 + Rv3311 0.78 -1.6
3,699,105 + Rv3311 0.78 -0.6
3,699,106 - Rv3311 0.78 -0.4
3,699,273 + -0.3
3,699,273 + -0.8
3,699,273 + -1.5
3,699,274 - -0.7
3,699,274 - +1.9
3,699,405 + +0.2
3,699,532 - Rv3312c 0.14 +1.3
3,699,580 + Rv3312c 0.19 -0.2
3,699,580 + Rv3312c 0.19 -1.3
3,699,586 + Rv3312c 0.20 -0.2
3,699,586 + Rv3312c 0.20 -0.6
3,699,645 + Rv3312c 0.26 -0.2
3,699,645 + Rv3312c 0.26 -0.1
3,699,645 + Rv3312c 0.26 -0.6
3,699,646 - Rv3312c 0.26 -1.3
3,699,646 - Rv3312c 0.26 +0.7
3,699,646 - Rv3312c 0.26 -0.3
3,699,766 + Rv3312c 0.39 -0.1
3,699,766 + Rv3312c 0.39 +1.5
3,699,787 - Rv3312c 0.41 +1.9
3,699,858 + Rv3312c 0.49 -0.1
3,699,859 - Rv3312c 0.49 +0.0
3,700,104 + Rv3312c 0.76 +0.1
3,700,125 - Rv3312c 0.78 -0.2
3,700,203 + Rv3312c 0.86 -0.6
3,700,204 - Rv3312c 0.86 +1.9
3,700,243 - +0.2
3,700,348 + +0.2
3,700,349 - +0.5
3,700,349 - +0.1

Or see this region's nucleotide sequence