Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3192

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntGFF3322 and Rv3192 are separated by 119 nucleotidesRv3192 and Rv3193c are separated by 169 nucleotides GFF3322 - tRNA-Met, at 3,559,370 to 3,559,443 GFF3322 Rv3192: Rv3192 - Conserved hypothetical alanine and proline-rich protein, at 3,559,563 to 3,560,024 Rv3192 Rv3193c: Rv3193c - Probable conserved transmembrane protein, at 3,560,194 to 3,563,172 Rv3193c Position (kb) 3559 3560 3561Strain fitness (log2 ratio) -1 0 1at 3558.693 kb on + strandat 3558.729 kb on + strandat 3558.744 kb on - strandat 3558.864 kb on - strandat 3558.864 kb on - strandat 3558.918 kb on - strandat 3558.936 kb on - strandat 3559.049 kb on - strandat 3559.162 kb on + strandat 3559.195 kb on - strandat 3559.296 kb on - strandat 3559.533 kb on + strandat 3559.534 kb on - strandat 3559.775 kb on + strand, within Rv3192at 3559.776 kb on - strand, within Rv3192at 3559.837 kb on - strand, within Rv3192at 3559.841 kb on + strand, within Rv3192at 3559.875 kb on + strand, within Rv3192at 3559.876 kb on - strand, within Rv3192at 3560.341 kb on + strandat 3560.615 kb on + strand, within Rv3193cat 3560.940 kb on - strand, within Rv3193c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,558,693 + +0.1
3,558,729 + -0.6
3,558,744 - -0.3
3,558,864 - -0.5
3,558,864 - -1.2
3,558,918 - +0.2
3,558,936 - -0.2
3,559,049 - -0.4
3,559,162 + -0.5
3,559,195 - -0.9
3,559,296 - +0.8
3,559,533 + -1.1
3,559,534 - +0.6
3,559,775 + Rv3192 0.46 -0.4
3,559,776 - Rv3192 0.46 -0.4
3,559,837 - Rv3192 0.59 -1.3
3,559,841 + Rv3192 0.60 -0.6
3,559,875 + Rv3192 0.68 -1.0
3,559,876 - Rv3192 0.68 -0.6
3,560,341 + -0.9
3,560,615 + Rv3193c 0.14 -0.4
3,560,940 - Rv3193c 0.25 +0.0

Or see this region's nucleotide sequence