Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3182

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3180c and Rv3181c are separated by 2 nucleotidesRv3181c and Rv3182 are separated by 230 nucleotidesRv3182 and Rv3183 overlap by 4 nucleotidesRv3183 and Rv3184 are separated by 236 nucleotidesRv3184 and Rv3185 overlap by 52 nucleotides Rv3180c: Rv3180c - Hypothetical alanine rich protein, at 3,549,254 to 3,549,688 Rv3180c Rv3181c: Rv3181c - Conserved protein, at 3,549,691 to 3,550,143 Rv3181c Rv3182: Rv3182 - Conserved hypothetical protein, at 3,550,374 to 3,550,718 Rv3182 Rv3183: Rv3183 - Possible transcriptional regulatory protein, at 3,550,715 to 3,551,044 Rv3183 Rv3184: Rv3184 - Probable transposase for insertion sequence element IS6110 (fragment), at 3,551,281 to 3,551,607 Rv3184 Rv3185: Rv3185 - Probable transposase, at 3,551,556 to 3,552,542 Rv3185 Position (kb) 3550 3551Strain fitness (log2 ratio) -1 0 1 2 3at 3549.395 kb on + strand, within Rv3180cat 3549.518 kb on + strand, within Rv3180cat 3549.519 kb on - strand, within Rv3180cat 3549.608 kb on + strand, within Rv3180cat 3549.609 kb on - strand, within Rv3180cat 3549.675 kb on + strandat 3549.944 kb on - strand, within Rv3181cat 3550.257 kb on - strandat 3550.345 kb on - strandat 3550.468 kb on - strand, within Rv3182at 3551.047 kb on + strandat 3551.133 kb on - strandat 3551.133 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,549,395 + Rv3180c 0.32 -0.7
3,549,518 + Rv3180c 0.61 -0.4
3,549,519 - Rv3180c 0.61 -0.6
3,549,608 + Rv3180c 0.81 +0.6
3,549,609 - Rv3180c 0.82 -0.1
3,549,675 + -1.0
3,549,944 - Rv3181c 0.56 -0.2
3,550,257 - -0.4
3,550,345 - -0.1
3,550,468 - Rv3182 0.27 -0.9
3,551,047 + -0.0
3,551,133 - -0.3
3,551,133 - +2.9

Or see this region's nucleotide sequence