Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3140

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3139 and Rv3140 are separated by 20 nucleotidesRv3140 and Rv3141 are separated by 99 nucleotides Rv3139: Rv3139 - Probable acyl-CoA dehydrogenase FadE24, at 3,505,363 to 3,506,769 Rv3139 Rv3140: Rv3140 - Probable acyl-CoA dehydrogenase FadE23, at 3,506,790 to 3,507,995 Rv3140 Rv3141: Rv3141 - Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin), at 3,508,095 to 3,509,066 Rv3141 Position (kb) 3506 3507 3508Strain fitness (log2 ratio) -2 -1 0 1 2at 3505.825 kb on - strand, within Rv3139at 3505.825 kb on - strand, within Rv3139at 3505.913 kb on - strand, within Rv3139at 3506.178 kb on + strand, within Rv3139at 3506.179 kb on - strand, within Rv3139at 3506.440 kb on + strand, within Rv3139at 3506.689 kb on + strandat 3506.690 kb on - strandat 3506.907 kb on + strandat 3507.046 kb on + strand, within Rv3140at 3507.357 kb on - strand, within Rv3140at 3507.357 kb on - strand, within Rv3140at 3507.612 kb on - strand, within Rv3140at 3507.646 kb on - strand, within Rv3140at 3508.225 kb on + strand, within Rv3141at 3508.246 kb on - strand, within Rv3141at 3508.470 kb on + strand, within Rv3141at 3508.471 kb on - strand, within Rv3141at 3508.723 kb on + strand, within Rv3141at 3508.871 kb on - strand, within Rv3141at 3508.943 kb on - strand, within Rv3141at 3508.943 kb on - strand, within Rv3141at 3508.980 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,505,825 - Rv3139 0.33 -1.4
3,505,825 - Rv3139 0.33 -0.3
3,505,913 - Rv3139 0.39 -2.1
3,506,178 + Rv3139 0.58 -0.8
3,506,179 - Rv3139 0.58 -0.6
3,506,440 + Rv3139 0.77 -0.8
3,506,689 + -1.3
3,506,690 - -1.1
3,506,907 + -0.9
3,507,046 + Rv3140 0.21 -1.3
3,507,357 - Rv3140 0.47 -2.1
3,507,357 - Rv3140 0.47 -0.4
3,507,612 - Rv3140 0.68 -1.6
3,507,646 - Rv3140 0.71 -0.3
3,508,225 + Rv3141 0.13 +0.1
3,508,246 - Rv3141 0.16 -0.7
3,508,470 + Rv3141 0.39 +1.9
3,508,471 - Rv3141 0.39 -0.5
3,508,723 + Rv3141 0.65 +0.9
3,508,871 - Rv3141 0.80 -0.4
3,508,943 - Rv3141 0.87 -0.2
3,508,943 - Rv3141 0.87 +0.2
3,508,980 + +0.7

Or see this region's nucleotide sequence