Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3131

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3130c and Rv3131 are separated by 184 nucleotidesRv3131 and Rv3132c overlap by 21 nucleotides Rv3130c: Rv3130c - Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1, at 3,494,975 to 3,496,366 Rv3130c Rv3131: Rv3131 - Conserved protein, at 3,496,551 to 3,497,549 Rv3131 Rv3132c: Rv3132c - Two component sensor histidine kinase DevS, at 3,497,529 to 3,499,265 Rv3132c Position (kb) 3496 3497 3498Strain fitness (log2 ratio) -1 0 1at 3495.899 kb on - strand, within Rv3130cat 3496.191 kb on - strand, within Rv3130cat 3496.220 kb on + strand, within Rv3130cat 3496.220 kb on + strand, within Rv3130cat 3496.355 kb on + strandat 3496.356 kb on - strandat 3496.513 kb on - strandat 3496.679 kb on + strand, within Rv3131at 3497.959 kb on - strand, within Rv3132c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,495,899 - Rv3130c 0.66 -0.0
3,496,191 - Rv3130c 0.87 -0.3
3,496,220 + Rv3130c 0.89 -0.5
3,496,220 + Rv3130c 0.89 +0.0
3,496,355 + -0.5
3,496,356 - -0.1
3,496,513 - -1.5
3,496,679 + Rv3131 0.13 -1.0
3,497,959 - Rv3132c 0.25 -0.8

Or see this region's nucleotide sequence