Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2920c

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2918c and Rv2919c are separated by 57 nucleotidesRv2919c and Rv2920c overlap by 4 nucleotidesRv2920c and Rv2921c are separated by 364 nucleotides Rv2918c: Rv2918c - Probable [protein-PII] uridylyltransferase GlnD (PII uridylyl-transferase) (uridylyl removing enzyme) (UTASE), at 3,228,254 to 3,230,680 Rv2918c Rv2919c: Rv2919c - Probable nitrogen regulatory protein P-II GlnB, at 3,230,738 to 3,231,076 Rv2919c Rv2920c: Rv2920c - Probable ammonium-transport integral membrane protein Amt, at 3,231,073 to 3,232,506 Rv2920c Rv2921c: Rv2921c - Probable cell division protein FtsY (SRP receptor) (signal recognition particle receptor), at 3,232,871 to 3,234,139 Rv2921c Position (kb) 3231 3232 3233Strain fitness (log2 ratio) -1 0 1 2at 3230.940 kb on + strand, within Rv2919cat 3231.103 kb on + strandat 3231.103 kb on + strandat 3231.104 kb on - strandat 3231.105 kb on + strandat 3231.105 kb on + strandat 3231.106 kb on - strandat 3231.362 kb on + strand, within Rv2920cat 3231.646 kb on - strand, within Rv2920cat 3232.176 kb on + strand, within Rv2920cat 3232.251 kb on - strand, within Rv2920cat 3232.310 kb on + strand, within Rv2920cat 3232.311 kb on - strand, within Rv2920cat 3232.311 kb on - strand, within Rv2920cat 3232.401 kb on - strandat 3232.583 kb on - strandat 3232.583 kb on - strandat 3232.583 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,230,940 + Rv2919c 0.60 -0.1
3,231,103 + +0.6
3,231,103 + -1.0
3,231,104 - -0.5
3,231,105 + -0.4
3,231,105 + +1.9
3,231,106 - +0.2
3,231,362 + Rv2920c 0.20 -1.4
3,231,646 - Rv2920c 0.40 -1.0
3,232,176 + Rv2920c 0.77 -0.0
3,232,251 - Rv2920c 0.82 -0.8
3,232,310 + Rv2920c 0.86 -0.4
3,232,311 - Rv2920c 0.86 -0.0
3,232,311 - Rv2920c 0.86 +0.2
3,232,401 - +0.3
3,232,583 - -0.1
3,232,583 - +0.2
3,232,583 - +0.9

Or see this region's nucleotide sequence