Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2831

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2828c and Rv2828A overlap by 4 nucleotidesRv2828A and Rv2829c are separated by 20 nucleotidesRv2829c and Rv2830c overlap by 4 nucleotidesRv2830c and Rv2831 are separated by 46 nucleotidesRv2831 and Rv2832c are separated by 78 nucleotides Rv2828c: Rv2828c - Conserved hypothetical protein, at 3,135,788 to 3,136,333 Rv2828c Rv2828A: Rv2828A - Conserved hypothetical protein, at 3,136,330 to 3,136,599 Rv2828A Rv2829c: Rv2829c - Possible toxin VapC22, at 3,136,620 to 3,137,012 Rv2829c Rv2830c: Rv2830c - Possible antitoxin VapB22, at 3,137,009 to 3,137,224 Rv2830c Rv2831: Rv2831 - Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 3,137,271 to 3,138,020 Rv2831 Rv2832c: Rv2832c - Probable Sn-glycerol-3-phosphate transport ATP-binding protein ABC transporter UgpC, at 3,138,099 to 3,139,181 Rv2832c Position (kb) 3137 3138 3139Strain fitness (log2 ratio) -1 0 1at 3136.521 kb on - strand, within Rv2828Aat 3136.711 kb on + strand, within Rv2829cat 3136.712 kb on - strand, within Rv2829cat 3137.365 kb on + strand, within Rv2831at 3137.593 kb on - strand, within Rv2831at 3137.740 kb on - strand, within Rv2831

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,136,521 - Rv2828A 0.71 +1.1
3,136,711 + Rv2829c 0.23 -0.3
3,136,712 - Rv2829c 0.23 +0.1
3,137,365 + Rv2831 0.13 -0.6
3,137,593 - Rv2831 0.43 -1.2
3,137,740 - Rv2831 0.63 -0.4

Or see this region's nucleotide sequence