Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2317

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2315c and Rv2316 are separated by 33 nucleotidesRv2316 and Rv2317 overlap by 14 nucleotidesRv2317 and Rv2318 overlap by 4 nucleotides Rv2315c: Rv2315c - Conserved protein, at 2,587,287 to 2,588,804 Rv2315c Rv2316: Rv2316 - Probable sugar-transport integral membrane protein ABC transporter UspA, at 2,588,838 to 2,589,710 Rv2316 Rv2317: Rv2317 - Probable sugar-transport integral membrane protein ABC transporter UspB, at 2,589,697 to 2,590,521 Rv2317 Rv2318: Rv2318 - Probable periplasmic sugar-binding lipoprotein UspC, at 2,590,518 to 2,591,840 Rv2318 Position (kb) 2589 2590 2591Strain fitness (log2 ratio) -2 -1 0 1at 2588.815 kb on + strandat 2588.829 kb on - strandat 2588.874 kb on + strandat 2588.874 kb on + strandat 2588.875 kb on - strandat 2588.941 kb on + strand, within Rv2316at 2588.941 kb on + strand, within Rv2316at 2588.942 kb on - strand, within Rv2316at 2588.942 kb on - strand, within Rv2316at 2589.091 kb on + strand, within Rv2316at 2589.159 kb on + strand, within Rv2316at 2589.160 kb on - strand, within Rv2316at 2589.362 kb on - strand, within Rv2316at 2589.676 kb on - strandat 2589.709 kb on - strandat 2590.025 kb on - strand, within Rv2317at 2590.640 kb on - strandat 2590.755 kb on + strand, within Rv2318at 2590.836 kb on + strand, within Rv2318at 2591.187 kb on + strand, within Rv2318at 2591.391 kb on + strand, within Rv2318at 2591.392 kb on - strand, within Rv2318

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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2,588,815 + +0.5
2,588,829 - -0.1
2,588,874 + -1.3
2,588,874 + +0.5
2,588,875 - -1.3
2,588,941 + Rv2316 0.12 -0.4
2,588,941 + Rv2316 0.12 +0.2
2,588,942 - Rv2316 0.12 -1.9
2,588,942 - Rv2316 0.12 +0.0
2,589,091 + Rv2316 0.29 +0.6
2,589,159 + Rv2316 0.37 +0.2
2,589,160 - Rv2316 0.37 -0.6
2,589,362 - Rv2316 0.60 +0.9
2,589,676 - -0.8
2,589,709 - -0.4
2,590,025 - Rv2317 0.40 -1.0
2,590,640 - -0.1
2,590,755 + Rv2318 0.18 -0.1
2,590,836 + Rv2318 0.24 +0.3
2,591,187 + Rv2318 0.51 +0.5
2,591,391 + Rv2318 0.66 -0.8
2,591,392 - Rv2318 0.66 -0.5

Or see this region's nucleotide sequence