Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2206

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2205c and Rv2206 are separated by 158 nucleotidesRv2206 and Rv2207 are separated by 78 nucleotides Rv2205c: Rv2205c - Conserved hypothetical protein, at 2,469,387 to 2,470,463 Rv2205c Rv2206: Rv2206 - Probable conserved transmembrane protein, at 2,470,622 to 2,471,332 Rv2206 Rv2207: Rv2207 - Probable nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase CobT, at 2,471,411 to 2,472,496 Rv2207 Position (kb) 2470 2471 2472Strain fitness (log2 ratio) -2 -1 0 1 2at 2470.046 kb on + strand, within Rv2205cat 2470.047 kb on - strand, within Rv2205cat 2470.047 kb on - strand, within Rv2205cat 2470.208 kb on - strand, within Rv2205cat 2470.545 kb on + strandat 2470.545 kb on + strandat 2470.546 kb on - strandat 2470.546 kb on - strandat 2470.546 kb on - strandat 2470.571 kb on + strandat 2470.609 kb on + strandat 2470.980 kb on - strand, within Rv2206at 2471.142 kb on + strand, within Rv2206at 2471.142 kb on + strand, within Rv2206at 2471.142 kb on + strand, within Rv2206at 2471.361 kb on + strandat 2471.362 kb on - strandat 2471.362 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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2,470,046 + Rv2205c 0.61 -0.9
2,470,047 - Rv2205c 0.61 +0.1
2,470,047 - Rv2205c 0.61 +2.4
2,470,208 - Rv2205c 0.76 -1.1
2,470,545 + +0.7
2,470,545 + -0.7
2,470,546 - -0.8
2,470,546 - -0.4
2,470,546 - +1.6
2,470,571 + -0.7
2,470,609 + -0.1
2,470,980 - Rv2206 0.50 -0.4
2,471,142 + Rv2206 0.73 -0.7
2,471,142 + Rv2206 0.73 -1.9
2,471,142 + Rv2206 0.73 -0.2
2,471,361 + -1.1
2,471,362 - -2.6
2,471,362 - -0.0

Or see this region's nucleotide sequence