Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1834

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1833c and Rv1834 are separated by 40 nucleotidesRv1834 and Rv1835c are separated by 4 nucleotides Rv1833c: Rv1833c - Possible haloalkane dehalogenase, at 2,078,929 to 2,079,789 Rv1833c Rv1834: Rv1834 - Probable hydrolase, at 2,079,830 to 2,080,696 Rv1834 Rv1835c: Rv1835c - Conserved hypothetical protein, at 2,080,701 to 2,082,587 Rv1835c Position (kb) 2079 2080 2081Strain fitness (log2 ratio) -2 -1 0 1 2at 2078.865 kb on + strandat 2078.866 kb on - strandat 2079.191 kb on - strand, within Rv1833cat 2079.250 kb on - strand, within Rv1833cat 2079.641 kb on + strand, within Rv1833cat 2079.642 kb on - strand, within Rv1833cat 2079.790 kb on + strandat 2080.281 kb on + strand, within Rv1834at 2080.282 kb on - strand, within Rv1834at 2080.282 kb on - strand, within Rv1834at 2080.457 kb on + strand, within Rv1834at 2080.458 kb on - strand, within Rv1834at 2080.458 kb on - strand, within Rv1834at 2080.661 kb on + strandat 2080.662 kb on - strandat 2080.710 kb on + strandat 2080.710 kb on + strandat 2080.711 kb on - strandat 2080.711 kb on - strandat 2080.753 kb on + strandat 2080.852 kb on + strandat 2080.853 kb on - strandat 2080.853 kb on - strandat 2080.902 kb on + strand, within Rv1835cat 2080.995 kb on + strand, within Rv1835cat 2080.995 kb on + strand, within Rv1835cat 2080.996 kb on - strand, within Rv1835cat 2080.996 kb on - strand, within Rv1835cat 2080.996 kb on - strand, within Rv1835cat 2081.014 kb on + strand, within Rv1835cat 2081.015 kb on - strand, within Rv1835cat 2081.015 kb on - strand, within Rv1835cat 2081.051 kb on - strand, within Rv1835cat 2081.088 kb on - strand, within Rv1835cat 2081.088 kb on - strand, within Rv1835cat 2081.147 kb on + strand, within Rv1835cat 2081.148 kb on - strand, within Rv1835cat 2081.149 kb on + strand, within Rv1835cat 2081.150 kb on - strand, within Rv1835cat 2081.150 kb on - strand, within Rv1835cat 2081.150 kb on - strand, within Rv1835cat 2081.266 kb on + strand, within Rv1835cat 2081.266 kb on + strand, within Rv1835cat 2081.266 kb on + strand, within Rv1835cat 2081.267 kb on - strand, within Rv1835cat 2081.330 kb on - strand, within Rv1835cat 2081.332 kb on + strand, within Rv1835cat 2081.332 kb on + strand, within Rv1835cat 2081.332 kb on + strand, within Rv1835cat 2081.333 kb on - strand, within Rv1835cat 2081.333 kb on - strand, within Rv1835cat 2081.333 kb on - strand, within Rv1835cat 2081.333 kb on - strand, within Rv1835cat 2081.402 kb on - strand, within Rv1835cat 2081.614 kb on + strand, within Rv1835cat 2081.615 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.680 kb on + strand, within Rv1835c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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2,078,865 + +0.6
2,078,866 - -2.1
2,079,191 - Rv1833c 0.30 -0.2
2,079,250 - Rv1833c 0.37 -0.6
2,079,641 + Rv1833c 0.83 +1.7
2,079,642 - Rv1833c 0.83 -0.4
2,079,790 + +0.1
2,080,281 + Rv1834 0.52 -1.1
2,080,282 - Rv1834 0.52 -0.5
2,080,282 - Rv1834 0.52 -0.8
2,080,457 + Rv1834 0.72 -0.3
2,080,458 - Rv1834 0.72 -0.3
2,080,458 - Rv1834 0.72 -0.4
2,080,661 + -0.2
2,080,662 - -0.2
2,080,710 + -1.5
2,080,710 + -0.1
2,080,711 - -0.1
2,080,711 - -0.1
2,080,753 + -1.7
2,080,852 + -0.3
2,080,853 - +0.6
2,080,853 - +0.3
2,080,902 + Rv1835c 0.11 +0.9
2,080,995 + Rv1835c 0.16 +0.7
2,080,995 + Rv1835c 0.16 -0.5
2,080,996 - Rv1835c 0.16 +0.4
2,080,996 - Rv1835c 0.16 +0.0
2,080,996 - Rv1835c 0.16 -0.6
2,081,014 + Rv1835c 0.17 +0.3
2,081,015 - Rv1835c 0.17 +0.8
2,081,015 - Rv1835c 0.17 -0.0
2,081,051 - Rv1835c 0.19 +0.4
2,081,088 - Rv1835c 0.21 -0.0
2,081,088 - Rv1835c 0.21 -0.7
2,081,147 + Rv1835c 0.24 -0.2
2,081,148 - Rv1835c 0.24 -0.3
2,081,149 + Rv1835c 0.24 -0.4
2,081,150 - Rv1835c 0.24 -0.4
2,081,150 - Rv1835c 0.24 -0.1
2,081,150 - Rv1835c 0.24 -0.4
2,081,266 + Rv1835c 0.30 +0.1
2,081,266 + Rv1835c 0.30 +0.5
2,081,266 + Rv1835c 0.30 -0.1
2,081,267 - Rv1835c 0.30 -0.1
2,081,330 - Rv1835c 0.33 -0.6
2,081,332 + Rv1835c 0.33 +0.1
2,081,332 + Rv1835c 0.33 -0.4
2,081,332 + Rv1835c 0.33 -0.0
2,081,333 - Rv1835c 0.33 -0.5
2,081,333 - Rv1835c 0.33 +0.1
2,081,333 - Rv1835c 0.33 -0.2
2,081,333 - Rv1835c 0.33 +0.1
2,081,402 - Rv1835c 0.37 +0.3
2,081,614 + Rv1835c 0.48 -0.6
2,081,615 - Rv1835c 0.48 -1.0
2,081,639 - Rv1835c 0.50 +0.5
2,081,639 - Rv1835c 0.50 -1.3
2,081,639 - Rv1835c 0.50 +1.8
2,081,680 + Rv1835c 0.52 +0.1

Or see this region's nucleotide sequence