Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1692

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1690 and Rv1691 are separated by 38 nucleotidesRv1691 and Rv1692 overlap by 4 nucleotidesRv1692 and Rv1693 overlap by 4 nucleotidesRv1693 and Rv1694 are separated by 7 nucleotidesRv1694 and Rv1695 overlap by 1 nucleotides Rv1690: Rv1690 - Probable lipoprotein LprJ, at 1,915,527 to 1,915,910 Rv1690 Rv1691: Rv1691 - Conserved hypothetical protein, at 1,915,949 to 1,916,701 Rv1691 Rv1692: Rv1692 - Probable phosphatase, at 1,916,698 to 1,917,759 Rv1692 Rv1693: Rv1693 - Conserved hypothetical protein, at 1,917,756 to 1,917,932 Rv1693 Rv1694: Rv1694 - 2'-O-methyltransferase TlyA, at 1,917,940 to 1,918,746 Rv1694 Rv1695: Rv1695 - Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase), at 1,918,746 to 1,919,669 Rv1695 Position (kb) 1916 1917 1918Strain fitness (log2 ratio) -1 0 1at 1915.832 kb on + strand, within Rv1690at 1915.833 kb on - strand, within Rv1690at 1915.915 kb on + strandat 1916.137 kb on - strand, within Rv1691at 1916.139 kb on + strand, within Rv1691at 1916.619 kb on + strand, within Rv1691at 1916.679 kb on + strandat 1916.844 kb on + strand, within Rv1692at 1917.415 kb on + strand, within Rv1692at 1917.442 kb on + strand, within Rv1692at 1917.442 kb on + strand, within Rv1692at 1917.442 kb on + strand, within Rv1692at 1917.443 kb on - strand, within Rv1692at 1917.742 kb on - strandat 1917.742 kb on - strandat 1917.747 kb on - strandat 1917.747 kb on - strandat 1917.799 kb on + strand, within Rv1693at 1917.800 kb on - strand, within Rv1693at 1918.148 kb on + strand, within Rv1694at 1918.654 kb on + strand, within Rv1694

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,915,832 + Rv1690 0.79 -0.5
1,915,833 - Rv1690 0.80 +0.4
1,915,915 + -0.1
1,916,137 - Rv1691 0.25 +0.4
1,916,139 + Rv1691 0.25 +0.1
1,916,619 + Rv1691 0.89 +0.6
1,916,679 + +0.3
1,916,844 + Rv1692 0.14 -1.4
1,917,415 + Rv1692 0.68 -0.7
1,917,442 + Rv1692 0.70 -0.7
1,917,442 + Rv1692 0.70 +0.5
1,917,442 + Rv1692 0.70 -0.6
1,917,443 - Rv1692 0.70 +0.4
1,917,742 - -0.7
1,917,742 - -0.2
1,917,747 - +0.1
1,917,747 - -0.2
1,917,799 + Rv1693 0.24 -0.5
1,917,800 - Rv1693 0.25 -0.9
1,918,148 + Rv1694 0.26 +0.1
1,918,654 + Rv1694 0.88 +0.6

Or see this region's nucleotide sequence