Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1618

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1617 and Rv1618 are separated by 7 nucleotidesRv1618 and Rv1619 are separated by 57 nucleotides Rv1617: Rv1617 - Probable pyruvate kinase PykA, at 1,816,189 to 1,817,607 Rv1617 Rv1618: Rv1618 - Probable acyl-CoA thioesterase II TesB1, at 1,817,615 to 1,818,517 Rv1618 Rv1619: Rv1619 - Conserved membrane protein, at 1,818,575 to 1,820,029 Rv1619 Position (kb) 1817 1818 1819Strain fitness (log2 ratio) -2 -1 0 1at 1817.606 kb on - strandat 1817.652 kb on + strandat 1817.653 kb on - strandat 1817.661 kb on + strandat 1817.868 kb on + strand, within Rv1618at 1817.954 kb on + strand, within Rv1618at 1817.954 kb on + strand, within Rv1618at 1817.954 kb on + strand, within Rv1618at 1817.954 kb on + strand, within Rv1618at 1817.954 kb on + strand, within Rv1618at 1817.955 kb on - strand, within Rv1618at 1817.955 kb on - strand, within Rv1618at 1817.955 kb on - strand, within Rv1618at 1818.017 kb on - strand, within Rv1618at 1818.105 kb on - strand, within Rv1618at 1818.156 kb on - strand, within Rv1618at 1818.156 kb on - strand, within Rv1618at 1818.156 kb on - strand, within Rv1618at 1818.227 kb on + strand, within Rv1618at 1818.262 kb on + strand, within Rv1618at 1818.365 kb on + strand, within Rv1618at 1818.366 kb on - strand, within Rv1618at 1818.476 kb on + strandat 1818.684 kb on + strandat 1818.685 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,817,606 - -0.4
1,817,652 + -2.5
1,817,653 - -0.6
1,817,661 + +0.5
1,817,868 + Rv1618 0.28 -0.2
1,817,954 + Rv1618 0.38 +0.2
1,817,954 + Rv1618 0.38 -0.2
1,817,954 + Rv1618 0.38 -1.0
1,817,954 + Rv1618 0.38 +0.7
1,817,954 + Rv1618 0.38 +1.7
1,817,955 - Rv1618 0.38 +0.4
1,817,955 - Rv1618 0.38 +0.3
1,817,955 - Rv1618 0.38 +0.9
1,818,017 - Rv1618 0.45 -2.0
1,818,105 - Rv1618 0.54 -0.2
1,818,156 - Rv1618 0.60 +1.0
1,818,156 - Rv1618 0.60 -0.4
1,818,156 - Rv1618 0.60 -0.1
1,818,227 + Rv1618 0.68 +0.3
1,818,262 + Rv1618 0.72 -0.1
1,818,365 + Rv1618 0.83 -0.0
1,818,366 - Rv1618 0.83 -1.1
1,818,476 + -0.2
1,818,684 + -0.7
1,818,685 - -0.4

Or see this region's nucleotide sequence