Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1410c

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1409 and Rv1410c overlap by 4 nucleotidesRv1410c and Rv1411c are separated by 5 nucleotidesRv1411c and Rv1412 are separated by 84 nucleotides Rv1409: Rv1409 - Probable bifunctional riboflavin biosynthesis protein RibG : diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase), at 1,585,194 to 1,586,213 Rv1409 Rv1410c: Rv1410c - Aminoglycosides/tetracycline-transport integral membrane protein, at 1,586,210 to 1,587,766 Rv1410c Rv1411c: Rv1411c - Conserved lipoprotein LprG, at 1,587,772 to 1,588,482 Rv1411c Rv1412: Rv1412 - Probable riboflavin synthase alpha chain RibC (RibE), at 1,588,567 to 1,589,172 Rv1412 Position (kb) 1586 1587 1588Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1586.212 kb on - strandat 1586.300 kb on + strandat 1586.301 kb on - strandat 1586.343 kb on - strandat 1586.343 kb on - strandat 1586.352 kb on + strandat 1586.352 kb on + strandat 1586.352 kb on + strandat 1586.466 kb on + strand, within Rv1410cat 1586.615 kb on + strand, within Rv1410cat 1586.713 kb on + strand, within Rv1410cat 1586.737 kb on + strand, within Rv1410cat 1587.077 kb on + strand, within Rv1410cat 1587.077 kb on + strand, within Rv1410cat 1587.077 kb on + strand, within Rv1410cat 1587.078 kb on - strand, within Rv1410cat 1587.105 kb on + strand, within Rv1410cat 1587.106 kb on - strand, within Rv1410cat 1587.218 kb on + strand, within Rv1410cat 1587.219 kb on - strand, within Rv1410cat 1587.219 kb on - strand, within Rv1410cat 1587.219 kb on - strand, within Rv1410cat 1587.413 kb on + strand, within Rv1410cat 1587.595 kb on - strand, within Rv1410cat 1587.595 kb on - strand, within Rv1410cat 1587.606 kb on + strand, within Rv1410cat 1587.607 kb on - strand, within Rv1410cat 1587.607 kb on - strand, within Rv1410cat 1587.652 kb on + strandat 1587.653 kb on - strandat 1587.653 kb on - strandat 1587.653 kb on - strandat 1587.653 kb on - strandat 1587.696 kb on + strandat 1587.696 kb on + strandat 1587.696 kb on + strandat 1587.697 kb on - strandat 1587.697 kb on - strandat 1587.697 kb on - strandat 1587.697 kb on - strandat 1587.697 kb on - strandat 1587.697 kb on - strandat 1587.720 kb on - strandat 1587.836 kb on + strandat 1587.943 kb on + strand, within Rv1411cat 1588.009 kb on - strand, within Rv1411cat 1588.095 kb on - strand, within Rv1411cat 1588.095 kb on - strand, within Rv1411cat 1588.148 kb on + strand, within Rv1411cat 1588.149 kb on - strand, within Rv1411cat 1588.185 kb on + strand, within Rv1411cat 1588.482 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,586,212 - -0.2
1,586,300 + -0.4
1,586,301 - +0.5
1,586,343 - -1.7
1,586,343 - -1.9
1,586,352 + -0.1
1,586,352 + -1.7
1,586,352 + -3.0
1,586,466 + Rv1410c 0.16 -1.2
1,586,615 + Rv1410c 0.26 -1.7
1,586,713 + Rv1410c 0.32 -2.8
1,586,737 + Rv1410c 0.34 -1.1
1,587,077 + Rv1410c 0.56 -1.8
1,587,077 + Rv1410c 0.56 +0.3
1,587,077 + Rv1410c 0.56 -1.3
1,587,078 - Rv1410c 0.56 -1.3
1,587,105 + Rv1410c 0.57 -2.4
1,587,106 - Rv1410c 0.58 -1.1
1,587,218 + Rv1410c 0.65 -2.0
1,587,219 - Rv1410c 0.65 -0.8
1,587,219 - Rv1410c 0.65 +0.4
1,587,219 - Rv1410c 0.65 -2.6
1,587,413 + Rv1410c 0.77 -1.7
1,587,595 - Rv1410c 0.89 -1.4
1,587,595 - Rv1410c 0.89 -0.8
1,587,606 + Rv1410c 0.90 -1.5
1,587,607 - Rv1410c 0.90 -1.7
1,587,607 - Rv1410c 0.90 -1.9
1,587,652 + -1.1
1,587,653 - -0.5
1,587,653 - -1.1
1,587,653 - -1.8
1,587,653 - -1.0
1,587,696 + -0.6
1,587,696 + -0.7
1,587,696 + +1.9
1,587,697 - -1.6
1,587,697 - -0.1
1,587,697 - -1.6
1,587,697 - -2.0
1,587,697 - -1.9
1,587,697 - -1.1
1,587,720 - -1.1
1,587,836 + -1.1
1,587,943 + Rv1411c 0.24 -0.5
1,588,009 - Rv1411c 0.33 +0.3
1,588,095 - Rv1411c 0.45 -2.5
1,588,095 - Rv1411c 0.45 +0.9
1,588,148 + Rv1411c 0.53 -1.1
1,588,149 - Rv1411c 0.53 -1.9
1,588,185 + Rv1411c 0.58 -0.9
1,588,482 + +1.1

Or see this region's nucleotide sequence