Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1324

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1323 and Rv1324 are separated by 129 nucleotidesRv1324 and Rv1325c are separated by 78 nucleotides Rv1323: Rv1323 - Probable acetyl-CoA acetyltransferase FadA4 (acetoacetyl-CoA thiolase), at 1,485,862 to 1,487,031 Rv1323 Rv1324: Rv1324 - Possible thioredoxin, at 1,487,161 to 1,488,075 Rv1324 Rv1325c: Rv1325c - PE-PGRS family protein PE_PGRS24, at 1,488,154 to 1,489,965 Rv1325c Position (kb) 1487 1488 1489Strain fitness (log2 ratio) -1 0 1 2at 1486.230 kb on + strand, within Rv1323at 1486.231 kb on - strand, within Rv1323at 1486.249 kb on + strand, within Rv1323at 1486.249 kb on + strand, within Rv1323at 1486.382 kb on - strand, within Rv1323at 1486.382 kb on - strand, within Rv1323at 1486.928 kb on + strandat 1486.928 kb on + strandat 1486.928 kb on + strandat 1486.929 kb on - strandat 1486.929 kb on - strandat 1486.929 kb on - strandat 1486.929 kb on - strandat 1486.929 kb on - strandat 1487.015 kb on + strandat 1487.015 kb on + strandat 1487.015 kb on + strandat 1487.087 kb on + strandat 1487.390 kb on + strand, within Rv1324at 1487.734 kb on + strand, within Rv1324

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,486,230 + Rv1323 0.31 +0.1
1,486,231 - Rv1323 0.32 -0.6
1,486,249 + Rv1323 0.33 +0.1
1,486,249 + Rv1323 0.33 +0.1
1,486,382 - Rv1323 0.44 -1.4
1,486,382 - Rv1323 0.44 +0.4
1,486,928 + -0.3
1,486,928 + +0.9
1,486,928 + +0.3
1,486,929 - -1.7
1,486,929 - -0.4
1,486,929 - +0.4
1,486,929 - -1.7
1,486,929 - -0.1
1,487,015 + +1.9
1,487,015 + -0.2
1,487,015 + -0.5
1,487,087 + -0.6
1,487,390 + Rv1324 0.25 +0.0
1,487,734 + Rv1324 0.63 -1.0

Or see this region's nucleotide sequence