Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1237

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1235 and Rv1236 overlap by 4 nucleotidesRv1236 and Rv1237 are separated by 4 nucleotidesRv1237 and Rv1238 are separated by 4 nucleotides Rv1235: Rv1235 - Probable sugar-binding lipoprotein LpqY, at 1,377,524 to 1,378,930 Rv1235 Rv1236: Rv1236 - Probable sugar-transport integral membrane protein ABC transporter SugA, at 1,378,927 to 1,379,850 Rv1236 Rv1237: Rv1237 - Probable sugar-transport integral membrane protein ABC transporter SugB, at 1,379,855 to 1,380,679 Rv1237 Rv1238: Rv1238 - Probable sugar-transport ATP-binding protein ABC transporter SugC, at 1,380,684 to 1,381,865 Rv1238 Position (kb) 1379 1380 1381Strain fitness (log2 ratio) -2 -1 0 1at 1379.066 kb on - strand, within Rv1236at 1379.079 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.141 kb on - strand, within Rv1236at 1379.141 kb on - strand, within Rv1236at 1379.165 kb on - strand, within Rv1236at 1379.335 kb on + strand, within Rv1236at 1379.337 kb on + strand, within Rv1236at 1379.338 kb on - strand, within Rv1236at 1379.338 kb on - strand, within Rv1236at 1379.348 kb on - strand, within Rv1236at 1379.348 kb on - strand, within Rv1236at 1379.473 kb on - strand, within Rv1236at 1379.656 kb on + strand, within Rv1236at 1379.657 kb on - strand, within Rv1236at 1379.657 kb on - strand, within Rv1236at 1379.657 kb on - strand, within Rv1236at 1380.011 kb on + strand, within Rv1237at 1380.011 kb on + strand, within Rv1237at 1380.011 kb on + strand, within Rv1237at 1380.012 kb on - strand, within Rv1237at 1380.305 kb on + strand, within Rv1237at 1380.306 kb on - strand, within Rv1237at 1380.827 kb on + strand, within Rv1238at 1380.937 kb on - strand, within Rv1238at 1380.953 kb on + strand, within Rv1238at 1381.252 kb on - strand, within Rv1238at 1381.300 kb on + strand, within Rv1238at 1381.569 kb on + strand, within Rv1238at 1381.644 kb on + strand, within Rv1238

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,379,066 - Rv1236 0.15 -0.2
1,379,079 + Rv1236 0.16 +0.9
1,379,140 + Rv1236 0.23 -0.0
1,379,140 + Rv1236 0.23 -0.4
1,379,140 + Rv1236 0.23 -1.4
1,379,141 - Rv1236 0.23 -0.5
1,379,141 - Rv1236 0.23 -0.6
1,379,165 - Rv1236 0.26 -2.4
1,379,335 + Rv1236 0.44 +0.3
1,379,337 + Rv1236 0.44 -0.8
1,379,338 - Rv1236 0.44 -0.1
1,379,338 - Rv1236 0.44 -0.4
1,379,348 - Rv1236 0.46 -0.1
1,379,348 - Rv1236 0.46 -0.4
1,379,473 - Rv1236 0.59 +0.0
1,379,656 + Rv1236 0.79 -0.4
1,379,657 - Rv1236 0.79 -0.2
1,379,657 - Rv1236 0.79 -1.4
1,379,657 - Rv1236 0.79 -0.2
1,380,011 + Rv1237 0.19 -1.1
1,380,011 + Rv1237 0.19 -0.1
1,380,011 + Rv1237 0.19 -0.8
1,380,012 - Rv1237 0.19 -0.2
1,380,305 + Rv1237 0.55 -1.8
1,380,306 - Rv1237 0.55 -0.4
1,380,827 + Rv1238 0.12 -0.7
1,380,937 - Rv1238 0.21 -0.1
1,380,953 + Rv1238 0.23 -0.5
1,381,252 - Rv1238 0.48 -0.2
1,381,300 + Rv1238 0.52 +0.1
1,381,569 + Rv1238 0.75 +0.1
1,381,644 + Rv1238 0.81 +1.1

Or see this region's nucleotide sequence