Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0769

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0768 and Rv0769 are separated by 30 nucleotidesRv0769 and Rv0770 are separated by 97 nucleotidesRv0770 and Rv0771 overlap by 4 nucleotides Rv0768: Rv0768 - Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]), at 860,912 to 862,381 Rv0768 Rv0769: Rv0769 - Probable dehydrogenase/reductase, at 862,412 to 863,158 Rv0769 Rv0770: Rv0770 - Probable dehydrogenase/reductase, at 863,256 to 864,143 Rv0770 Rv0771: Rv0771 - Possible 4-carboxymuconolactone decarboxylase (CMD), at 864,140 to 864,574 Rv0771 Position (kb) 862 863 864Strain fitness (log2 ratio) -2 -1 0 1at 861.951 kb on - strand, within Rv0768at 861.951 kb on - strand, within Rv0768at 862.661 kb on + strand, within Rv0769at 862.662 kb on - strand, within Rv0769at 862.777 kb on + strand, within Rv0769at 862.791 kb on - strand, within Rv0769at 862.938 kb on + strand, within Rv0769at 862.938 kb on + strand, within Rv0769at 863.289 kb on + strandat 863.291 kb on + strandat 863.291 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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861,951 - Rv0768 0.71 +0.3
861,951 - Rv0768 0.71 -0.2
862,661 + Rv0769 0.33 -2.1
862,662 - Rv0769 0.33 -0.5
862,777 + Rv0769 0.49 -0.9
862,791 - Rv0769 0.51 -0.1
862,938 + Rv0769 0.70 -0.2
862,938 + Rv0769 0.70 -0.5
863,289 + -0.0
863,291 + -0.4
863,291 + -0.4

Or see this region's nucleotide sequence