Experiment: L-Lactate 10 mM (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0501 and Rv0502 are separated by 6 nucleotides Rv0502 and Rv0503c are separated by 3 nucleotides Rv0503c and Rv0504c are separated by 22 nucleotides
Rv0501: Rv0501 - Possible UDP-glucose 4-epimerase GalE2 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 591,654 to 592,784
Rv0501
Rv0502: Rv0502 - Conserved protein, at 592,791 to 593,867
Rv0502
Rv0503c: Rv0503c - Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 2) (mycolic acid trans-cyclopropane synthetase), at 593,871 to 594,779
Rv0503c
Rv0504c: Rv0504c - Conserved protein, at 594,802 to 595,302
Rv0504c
Position (kb)
592
593
594 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 591.884 kb on + strand, within Rv0501 at 591.960 kb on + strand, within Rv0501 at 592.001 kb on + strand, within Rv0501 at 592.001 kb on + strand, within Rv0501 at 592.192 kb on - strand, within Rv0501 at 592.235 kb on + strand, within Rv0501 at 592.290 kb on + strand, within Rv0501 at 592.573 kb on - strand, within Rv0501 at 592.617 kb on + strand, within Rv0501 at 592.618 kb on - strand, within Rv0501 at 593.089 kb on - strand, within Rv0502 at 593.137 kb on + strand, within Rv0502 at 593.384 kb on + strand, within Rv0502 at 593.384 kb on + strand, within Rv0502 at 593.385 kb on - strand, within Rv0502 at 593.396 kb on + strand, within Rv0502 at 593.397 kb on - strand, within Rv0502 at 593.457 kb on + strand, within Rv0502 at 593.458 kb on - strand, within Rv0502 at 593.524 kb on + strand, within Rv0502 at 593.590 kb on - strand, within Rv0502 at 593.590 kb on - strand, within Rv0502 at 593.652 kb on - strand, within Rv0502 at 593.745 kb on + strand, within Rv0502 at 593.824 kb on + strand at 593.824 kb on + strand at 593.825 kb on - strand at 593.825 kb on - strand at 593.873 kb on - strand at 593.873 kb on - strand at 593.873 kb on - strand at 593.905 kb on + strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.906 kb on - strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.937 kb on + strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.938 kb on - strand at 593.941 kb on + strand at 593.942 kb on - strand at 593.942 kb on - strand at 593.950 kb on + strand at 593.950 kb on + strand at 593.950 kb on + strand at 593.951 kb on - strand at 593.951 kb on - strand at 593.951 kb on - strand at 593.959 kb on + strand at 593.959 kb on + strand at 593.960 kb on - strand at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.040 kb on + strand, within Rv0503c at 594.041 kb on - strand, within Rv0503c at 594.041 kb on - strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.094 kb on + strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.095 kb on - strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.097 kb on + strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.098 kb on - strand, within Rv0503c at 594.271 kb on + strand, within Rv0503c at 594.272 kb on - strand, within Rv0503c at 594.457 kb on + strand, within Rv0503c at 594.457 kb on + strand, within Rv0503c at 594.499 kb on + strand, within Rv0503c at 594.500 kb on - strand, within Rv0503c at 594.607 kb on + strand, within Rv0503c at 594.608 kb on - strand, within Rv0503c at 594.629 kb on + strand, within Rv0503c at 594.629 kb on + strand, within Rv0503c at 594.630 kb on - strand, within Rv0503c at 594.630 kb on - strand, within Rv0503c at 594.647 kb on - strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.658 kb on + strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.659 kb on - strand, within Rv0503c at 594.791 kb on + strand at 594.791 kb on + strand at 594.792 kb on - strand at 594.804 kb on - strand at 594.804 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C) remove 591,884 + Rv0501 0.20 -1.0 591,960 + Rv0501 0.27 +2.5 592,001 + Rv0501 0.31 -0.4 592,001 + Rv0501 0.31 +0.0 592,192 - Rv0501 0.48 -0.1 592,235 + Rv0501 0.51 -0.1 592,290 + Rv0501 0.56 -0.1 592,573 - Rv0501 0.81 +0.0 592,617 + Rv0501 0.85 -0.8 592,618 - Rv0501 0.85 -0.5 593,089 - Rv0502 0.28 -0.8 593,137 + Rv0502 0.32 -0.8 593,384 + Rv0502 0.55 +2.2 593,384 + Rv0502 0.55 -0.7 593,385 - Rv0502 0.55 -0.9 593,396 + Rv0502 0.56 -0.8 593,397 - Rv0502 0.56 -0.7 593,457 + Rv0502 0.62 -0.3 593,458 - Rv0502 0.62 -1.6 593,524 + Rv0502 0.68 -0.8 593,590 - Rv0502 0.74 -1.0 593,590 - Rv0502 0.74 -0.7 593,652 - Rv0502 0.80 +0.6 593,745 + Rv0502 0.89 -1.3 593,824 + +2.2 593,824 + -0.5 593,825 - -0.1 593,825 - -0.4 593,873 - -0.1 593,873 - -0.2 593,873 - +0.6 593,905 + -0.3 593,906 - +0.3 593,906 - +0.5 593,906 - -1.5 593,906 - +2.2 593,937 + -0.4 593,937 + -0.1 593,937 + -0.5 593,937 + -0.6 593,938 - -0.1 593,938 - -0.1 593,938 - +0.4 593,938 - -0.6 593,938 - +0.6 593,941 + -0.6 593,942 - +0.2 593,942 - -0.8 593,950 + -0.3 593,950 + -0.2 593,950 + -0.1 593,951 - +0.0 593,951 - +0.3 593,951 - +1.9 593,959 + +0.2 593,959 + +0.9 593,960 - -0.1 594,040 + Rv0503c 0.19 +0.1 594,040 + Rv0503c 0.19 -0.2 594,040 + Rv0503c 0.19 -1.5 594,040 + Rv0503c 0.19 -0.1 594,041 - Rv0503c 0.19 -0.4 594,041 - Rv0503c 0.19 +0.3 594,094 + Rv0503c 0.25 -0.1 594,094 + Rv0503c 0.25 -0.5 594,094 + Rv0503c 0.25 +0.4 594,094 + Rv0503c 0.25 -0.5 594,095 - Rv0503c 0.25 -1.6 594,095 - Rv0503c 0.25 -0.3 594,095 - Rv0503c 0.25 -0.0 594,097 + Rv0503c 0.25 -0.5 594,097 + Rv0503c 0.25 +2.5 594,097 + Rv0503c 0.25 +0.4 594,097 + Rv0503c 0.25 -0.8 594,098 - Rv0503c 0.25 -0.7 594,098 - Rv0503c 0.25 -0.6 594,098 - Rv0503c 0.25 -0.4 594,271 + Rv0503c 0.44 +0.0 594,272 - Rv0503c 0.44 +0.3 594,457 + Rv0503c 0.64 -0.1 594,457 + Rv0503c 0.64 +0.1 594,499 + Rv0503c 0.69 +0.3 594,500 - Rv0503c 0.69 -0.6 594,607 + Rv0503c 0.81 -0.3 594,608 - Rv0503c 0.81 +0.6 594,629 + Rv0503c 0.83 -0.0 594,629 + Rv0503c 0.83 -0.7 594,630 - Rv0503c 0.83 -0.9 594,630 - Rv0503c 0.83 -0.1 594,647 - Rv0503c 0.85 -0.2 594,658 + Rv0503c 0.87 +0.5 594,658 + Rv0503c 0.87 -0.5 594,658 + Rv0503c 0.87 -0.5 594,659 - Rv0503c 0.87 +0.4 594,659 - Rv0503c 0.87 -0.3 594,659 - Rv0503c 0.87 +0.1 594,659 - Rv0503c 0.87 -0.1 594,659 - Rv0503c 0.87 -0.1 594,791 + -0.1 594,791 + -1.0 594,792 - -0.3 594,804 - -1.8 594,804 - -0.4
Or see this region's nucleotide sequence