Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0220

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0218 and Rv0219 are separated by 1 nucleotidesRv0219 and Rv0220 are separated by 9 nucleotidesRv0220 and Rv0221 are separated by 43 nucleotides Rv0218: Rv0218 - Probable conserved transmembrane protein, at 260,924 to 262,252 Rv0218 Rv0219: Rv0219 - Probable conserved transmembrane protein, at 262,254 to 262,802 Rv0219 Rv0220: Rv0220 - Probable esterase LipC, at 262,812 to 264,023 Rv0220 Rv0221: Rv0221 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 264,067 to 265,476 Rv0221 Position (kb) 262 263 264 265Strain fitness (log2 ratio) -2 -1 0 1 2at 261.888 kb on + strand, within Rv0218at 262.048 kb on + strand, within Rv0218at 262.344 kb on + strand, within Rv0219at 262.551 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.632 kb on + strand, within Rv0219at 262.723 kb on - strand, within Rv0219at 262.868 kb on - strandat 262.889 kb on + strandat 262.890 kb on - strandat 263.246 kb on - strand, within Rv0220at 263.262 kb on - strand, within Rv0220at 263.631 kb on + strand, within Rv0220at 263.640 kb on + strand, within Rv0220at 264.039 kb on - strandat 264.313 kb on + strand, within Rv0221at 264.314 kb on - strand, within Rv0221at 264.427 kb on + strand, within Rv0221at 264.427 kb on + strand, within Rv0221at 264.428 kb on - strand, within Rv0221at 264.562 kb on + strand, within Rv0221at 264.583 kb on - strand, within Rv0221at 264.659 kb on - strand, within Rv0221at 264.659 kb on - strand, within Rv0221at 264.730 kb on - strand, within Rv0221at 264.898 kb on + strand, within Rv0221at 264.899 kb on - strand, within Rv0221

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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261,888 + Rv0218 0.73 +1.3
262,048 + Rv0218 0.85 -0.1
262,344 + Rv0219 0.16 -1.0
262,551 + Rv0219 0.54 -0.9
262,632 + Rv0219 0.69 -0.2
262,632 + Rv0219 0.69 -0.4
262,632 + Rv0219 0.69 -0.0
262,723 - Rv0219 0.85 -1.6
262,868 - +0.4
262,889 + -0.2
262,890 - +0.1
263,246 - Rv0220 0.36 -0.4
263,262 - Rv0220 0.37 -1.8
263,631 + Rv0220 0.68 -0.7
263,640 + Rv0220 0.68 -0.3
264,039 - -1.4
264,313 + Rv0221 0.17 -0.1
264,314 - Rv0221 0.18 -0.1
264,427 + Rv0221 0.26 +2.5
264,427 + Rv0221 0.26 -0.3
264,428 - Rv0221 0.26 +0.1
264,562 + Rv0221 0.35 -0.1
264,583 - Rv0221 0.37 -0.1
264,659 - Rv0221 0.42 +0.4
264,659 - Rv0221 0.42 +0.9
264,730 - Rv0221 0.47 -0.2
264,898 + Rv0221 0.59 +0.2
264,899 - Rv0221 0.59 +0.2

Or see this region's nucleotide sequence