Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0007

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0006 and Rv0007 are separated by 95 nucleotidesRv0007 and GFF8 are separated by 58 nucleotidesGFF8 and GFF9 are separated by 151 nucleotides Rv0006: Rv0006 - DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase), at 7,302 to 9,818 Rv0006 Rv0007: Rv0007 - Possible conserved membrane protein, at 9,914 to 10,828 Rv0007 GFF8 - tRNA-Ile, at 10,887 to 10,960 GFF8 GFF9 - tRNA-Ala, at 11,112 to 11,184 GFF9 Position (kb) 9 10 11Strain fitness (log2 ratio) -2 -1 0 1at 9.877 kb on + strandat 9.877 kb on + strandat 9.878 kb on - strandat 9.878 kb on - strandat 9.878 kb on - strandat 10.278 kb on - strand, within Rv0007at 11.289 kb on + strandat 11.290 kb on - strandat 11.422 kb on + strandat 11.422 kb on + strandat 11.557 kb on - strandat 11.619 kb on - strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.675 kb on + strandat 11.676 kb on - strandat 11.676 kb on - strandat 11.679 kb on + strandat 11.680 kb on - strandat 11.733 kb on + strandat 11.733 kb on + strandat 11.743 kb on + strandat 11.743 kb on + strandat 11.744 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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9,877 + -0.4
9,877 + -1.3
9,878 - -1.6
9,878 - -0.4
9,878 - -2.1
10,278 - Rv0007 0.40 -1.5
11,289 + -0.3
11,290 - -0.5
11,422 + +0.2
11,422 + +0.3
11,557 - +0.3
11,619 - -0.1
11,675 + -0.8
11,675 + -0.1
11,675 + -0.2
11,675 + +0.2
11,675 + -0.1
11,676 - +1.0
11,676 - -0.5
11,679 + +0.1
11,680 - -1.8
11,733 + +0.9
11,733 + +0.0
11,743 + -1.0
11,743 + -0.5
11,744 - +0.9

Or see this region's nucleotide sequence