Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3432c

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3431c and Rv3432c are separated by 232 nucleotidesRv3432c and Rv3433c are separated by 37 nucleotides Rv3431c: Rv3431c - Possible transposase (fragment), at 3,849,294 to 3,850,139 Rv3431c Rv3432c: Rv3432c - Probable glutamate decarboxylase GadB, at 3,850,372 to 3,851,754 Rv3432c Rv3433c: Rv3433c - Conserved protein, at 3,851,792 to 3,853,213 Rv3433c Position (kb) 3850 3851 3852Strain fitness (log2 ratio) -1 0 1 2 3at 3849.721 kb on + strand, within Rv3431cat 3849.722 kb on - strand, within Rv3431cat 3849.722 kb on - strand, within Rv3431cat 3849.809 kb on + strand, within Rv3431cat 3849.880 kb on + strand, within Rv3431cat 3849.880 kb on + strand, within Rv3431cat 3849.881 kb on - strand, within Rv3431cat 3850.275 kb on - strandat 3850.330 kb on + strandat 3850.330 kb on + strandat 3850.330 kb on + strandat 3850.330 kb on + strandat 3850.370 kb on + strandat 3850.371 kb on - strandat 3850.373 kb on + strandat 3850.373 kb on + strandat 3850.374 kb on - strandat 3850.374 kb on - strandat 3850.734 kb on + strand, within Rv3432cat 3850.734 kb on + strand, within Rv3432cat 3850.735 kb on - strand, within Rv3432cat 3850.735 kb on - strand, within Rv3432cat 3850.735 kb on - strand, within Rv3432cat 3850.735 kb on - strand, within Rv3432cat 3850.735 kb on - strand, within Rv3432cat 3850.736 kb on + strand, within Rv3432cat 3850.766 kb on + strand, within Rv3432cat 3850.766 kb on + strand, within Rv3432cat 3850.766 kb on + strand, within Rv3432cat 3850.767 kb on - strand, within Rv3432cat 3850.769 kb on + strand, within Rv3432cat 3850.769 kb on + strand, within Rv3432cat 3850.769 kb on + strand, within Rv3432cat 3850.839 kb on - strand, within Rv3432cat 3850.910 kb on + strand, within Rv3432cat 3850.922 kb on + strand, within Rv3432cat 3851.032 kb on + strand, within Rv3432cat 3851.032 kb on + strand, within Rv3432cat 3851.033 kb on - strand, within Rv3432cat 3851.112 kb on + strand, within Rv3432cat 3851.113 kb on - strand, within Rv3432cat 3851.114 kb on + strand, within Rv3432cat 3851.114 kb on + strand, within Rv3432cat 3851.114 kb on + strand, within Rv3432cat 3851.115 kb on - strand, within Rv3432cat 3851.115 kb on - strand, within Rv3432cat 3851.115 kb on - strand, within Rv3432cat 3851.193 kb on - strand, within Rv3432cat 3851.499 kb on + strand, within Rv3432cat 3851.595 kb on + strand, within Rv3432cat 3851.595 kb on + strand, within Rv3432cat 3851.630 kb on + strandat 3851.706 kb on - strandat 3851.706 kb on - strandat 3851.793 kb on + strandat 3851.793 kb on + strandat 3851.794 kb on - strandat 3851.794 kb on - strandat 3852.027 kb on + strand, within Rv3433cat 3852.531 kb on + strand, within Rv3433cat 3852.532 kb on - strand, within Rv3433cat 3852.532 kb on - strand, within Rv3433cat 3852.581 kb on - strand, within Rv3433c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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3,849,721 + Rv3431c 0.50 +0.6
3,849,722 - Rv3431c 0.51 +0.4
3,849,722 - Rv3431c 0.51 +0.7
3,849,809 + Rv3431c 0.61 -0.0
3,849,880 + Rv3431c 0.69 +0.1
3,849,880 + Rv3431c 0.69 +1.3
3,849,881 - Rv3431c 0.69 +1.0
3,850,275 - -0.8
3,850,330 + +0.3
3,850,330 + -0.6
3,850,330 + -0.4
3,850,330 + +0.1
3,850,370 + -0.9
3,850,371 - +2.1
3,850,373 + +1.5
3,850,373 + -0.1
3,850,374 - -0.2
3,850,374 - -0.4
3,850,734 + Rv3432c 0.26 +1.0
3,850,734 + Rv3432c 0.26 -0.0
3,850,735 - Rv3432c 0.26 -0.3
3,850,735 - Rv3432c 0.26 +1.8
3,850,735 - Rv3432c 0.26 -0.7
3,850,735 - Rv3432c 0.26 +0.6
3,850,735 - Rv3432c 0.26 -0.4
3,850,736 + Rv3432c 0.26 -0.1
3,850,766 + Rv3432c 0.28 -0.3
3,850,766 + Rv3432c 0.28 +2.5
3,850,766 + Rv3432c 0.28 -0.1
3,850,767 - Rv3432c 0.29 +0.9
3,850,769 + Rv3432c 0.29 -0.2
3,850,769 + Rv3432c 0.29 +0.0
3,850,769 + Rv3432c 0.29 +1.2
3,850,839 - Rv3432c 0.34 -0.2
3,850,910 + Rv3432c 0.39 +0.2
3,850,922 + Rv3432c 0.40 -0.1
3,851,032 + Rv3432c 0.48 +0.9
3,851,032 + Rv3432c 0.48 -0.1
3,851,033 - Rv3432c 0.48 -0.5
3,851,112 + Rv3432c 0.54 +0.4
3,851,113 - Rv3432c 0.54 +0.2
3,851,114 + Rv3432c 0.54 +0.3
3,851,114 + Rv3432c 0.54 -0.4
3,851,114 + Rv3432c 0.54 -1.0
3,851,115 - Rv3432c 0.54 +3.1
3,851,115 - Rv3432c 0.54 -0.1
3,851,115 - Rv3432c 0.54 -0.3
3,851,193 - Rv3432c 0.59 +1.8
3,851,499 + Rv3432c 0.81 -0.0
3,851,595 + Rv3432c 0.88 +1.8
3,851,595 + Rv3432c 0.88 +0.2
3,851,630 + -1.6
3,851,706 - -1.2
3,851,706 - -0.5
3,851,793 + +0.3
3,851,793 + +0.3
3,851,794 - -0.1
3,851,794 - +0.0
3,852,027 + Rv3433c 0.17 -1.0
3,852,531 + Rv3433c 0.52 +0.6
3,852,532 - Rv3433c 0.52 +1.8
3,852,532 - Rv3433c 0.52 +1.4
3,852,581 - Rv3433c 0.55 +0.5

Or see this region's nucleotide sequence