Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1330c

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1329c and Rv1330c are separated by 23 nucleotidesRv1330c and Rv1331 are separated by 101 nucleotidesRv1331 and Rv1332 overlap by 41 nucleotides Rv1329c: Rv1329c - Probable ATP-dependent helicase DinG, at 1,497,195 to 1,499,189 Rv1329c Rv1330c: Rv1330c - Nicotinic acid phosphoribosyltransferase PncB1, at 1,499,213 to 1,500,559 Rv1330c Rv1331: Rv1331 - Conserved hypothetical protein, at 1,500,661 to 1,500,966 Rv1331 Rv1332: Rv1332 - Probable transcriptional regulatory protein, at 1,500,926 to 1,501,582 Rv1332 Position (kb) 1499 1500 1501Strain fitness (log2 ratio) -3 -2 -1 0 1at 1498.243 kb on + strand, within Rv1329cat 1498.244 kb on - strand, within Rv1329cat 1498.382 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.670 kb on + strand, within Rv1329cat 1498.671 kb on - strand, within Rv1329cat 1499.015 kb on - strandat 1499.493 kb on + strand, within Rv1330cat 1499.494 kb on - strand, within Rv1330cat 1499.494 kb on - strand, within Rv1330cat 1499.516 kb on + strand, within Rv1330cat 1499.525 kb on + strand, within Rv1330cat 1499.541 kb on + strand, within Rv1330cat 1499.542 kb on - strand, within Rv1330cat 1499.599 kb on - strand, within Rv1330cat 1499.599 kb on - strand, within Rv1330cat 1499.684 kb on + strand, within Rv1330cat 1499.808 kb on + strand, within Rv1330cat 1499.808 kb on + strand, within Rv1330cat 1499.809 kb on - strand, within Rv1330cat 1499.812 kb on + strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1499.813 kb on - strand, within Rv1330cat 1500.003 kb on + strand, within Rv1330cat 1500.003 kb on + strand, within Rv1330cat 1500.481 kb on - strandat 1500.481 kb on - strandat 1500.481 kb on - strandat 1500.481 kb on - strandat 1500.694 kb on - strand, within Rv1331at 1500.694 kb on - strand, within Rv1331at 1500.784 kb on + strand, within Rv1331at 1500.793 kb on + strand, within Rv1331at 1500.794 kb on - strand, within Rv1331at 1500.794 kb on - strand, within Rv1331at 1501.347 kb on + strand, within Rv1332at 1501.347 kb on + strand, within Rv1332at 1501.523 kb on + strandat 1501.550 kb on + strandat 1501.551 kb on - strandat 1501.551 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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1,498,243 + Rv1329c 0.53 -0.4
1,498,244 - Rv1329c 0.53 -1.4
1,498,382 + Rv1329c 0.59 +1.0
1,498,670 + Rv1329c 0.74 -1.0
1,498,670 + Rv1329c 0.74 -0.9
1,498,670 + Rv1329c 0.74 -0.6
1,498,670 + Rv1329c 0.74 +0.2
1,498,671 - Rv1329c 0.74 -0.7
1,499,015 - +0.1
1,499,493 + Rv1330c 0.21 +0.0
1,499,494 - Rv1330c 0.21 +0.2
1,499,494 - Rv1330c 0.21 -0.8
1,499,516 + Rv1330c 0.22 -0.2
1,499,525 + Rv1330c 0.23 -0.2
1,499,541 + Rv1330c 0.24 -1.3
1,499,542 - Rv1330c 0.24 -0.5
1,499,599 - Rv1330c 0.29 -0.4
1,499,599 - Rv1330c 0.29 +0.2
1,499,684 + Rv1330c 0.35 +0.1
1,499,808 + Rv1330c 0.44 -1.9
1,499,808 + Rv1330c 0.44 -1.3
1,499,809 - Rv1330c 0.44 -1.2
1,499,812 + Rv1330c 0.44 -0.2
1,499,813 - Rv1330c 0.45 -0.3
1,499,813 - Rv1330c 0.45 -0.1
1,499,813 - Rv1330c 0.45 +0.7
1,500,003 + Rv1330c 0.59 +0.2
1,500,003 + Rv1330c 0.59 +1.4
1,500,481 - +0.0
1,500,481 - -1.7
1,500,481 - +0.2
1,500,481 - -0.4
1,500,694 - Rv1331 0.11 -1.0
1,500,694 - Rv1331 0.11 -1.1
1,500,784 + Rv1331 0.40 -1.1
1,500,793 + Rv1331 0.43 +1.7
1,500,794 - Rv1331 0.43 -1.3
1,500,794 - Rv1331 0.43 -1.8
1,501,347 + Rv1332 0.64 -0.7
1,501,347 + Rv1332 0.64 +0.2
1,501,523 + -1.2
1,501,550 + -1.1
1,501,551 - -0.7
1,501,551 - -2.9

Or see this region's nucleotide sequence