Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0330c

Experiment: L-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0328 and Rv0329c overlap by 20 nucleotidesRv0329c and Rv0330c are separated by 26 nucleotidesRv0330c and Rv0331 are separated by 113 nucleotides Rv0328: Rv0328 - Possible transcriptional regulatory protein (possibly TetR/AcrR-family), at 394,111 to 394,713 Rv0328 Rv0329c: Rv0329c - Conserved hypothetical protein, at 394,694 to 395,320 Rv0329c Rv0330c: Rv0330c - Hypothetical protein, at 395,347 to 396,087 Rv0330c Rv0331: Rv0331 - Possible dehydrogenase/reductase, at 396,201 to 397,367 Rv0331 Position (kb) 395 396 397Strain fitness (log2 ratio) -2 -1 0 1 2 3at 394.421 kb on - strand, within Rv0328at 394.421 kb on - strand, within Rv0328at 394.550 kb on + strand, within Rv0328at 394.551 kb on - strand, within Rv0328at 395.247 kb on - strand, within Rv0329cat 395.288 kb on + strandat 395.288 kb on + strandat 395.289 kb on - strandat 395.292 kb on + strandat 395.293 kb on - strandat 395.293 kb on - strandat 395.566 kb on + strand, within Rv0330cat 395.566 kb on + strand, within Rv0330cat 395.566 kb on + strand, within Rv0330cat 395.567 kb on - strand, within Rv0330cat 395.567 kb on - strand, within Rv0330cat 395.567 kb on - strand, within Rv0330cat 395.567 kb on - strand, within Rv0330cat 395.570 kb on + strand, within Rv0330cat 395.570 kb on + strand, within Rv0330cat 395.571 kb on - strand, within Rv0330cat 395.571 kb on - strand, within Rv0330cat 395.571 kb on - strand, within Rv0330cat 395.696 kb on + strand, within Rv0330cat 395.946 kb on - strand, within Rv0330cat 395.952 kb on - strand, within Rv0330cat 395.952 kb on - strand, within Rv0330cat 396.096 kb on - strandat 396.099 kb on - strandat 396.099 kb on - strandat 396.460 kb on + strand, within Rv0331at 396.461 kb on - strand, within Rv0331at 396.461 kb on - strand, within Rv0331at 396.512 kb on - strand, within Rv0331at 396.585 kb on + strand, within Rv0331at 396.872 kb on - strand, within Rv0331at 397.010 kb on - strand, within Rv0331at 397.038 kb on - strand, within Rv0331

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Lactate 10 mM (C)
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394,421 - Rv0328 0.51 +0.4
394,421 - Rv0328 0.51 -1.0
394,550 + Rv0328 0.73 -0.3
394,551 - Rv0328 0.73 -0.3
395,247 - Rv0329c 0.88 +3.0
395,288 + -0.0
395,288 + -1.0
395,289 - -0.2
395,292 + +1.8
395,293 - -0.6
395,293 - +0.4
395,566 + Rv0330c 0.30 -0.4
395,566 + Rv0330c 0.30 -0.4
395,566 + Rv0330c 0.30 -0.2
395,567 - Rv0330c 0.30 -0.3
395,567 - Rv0330c 0.30 -2.5
395,567 - Rv0330c 0.30 -0.8
395,567 - Rv0330c 0.30 -0.7
395,570 + Rv0330c 0.30 -0.6
395,570 + Rv0330c 0.30 -0.1
395,571 - Rv0330c 0.30 -0.6
395,571 - Rv0330c 0.30 +0.3
395,571 - Rv0330c 0.30 -0.6
395,696 + Rv0330c 0.47 +0.1
395,946 - Rv0330c 0.81 -0.3
395,952 - Rv0330c 0.82 +0.0
395,952 - Rv0330c 0.82 -0.0
396,096 - -0.4
396,099 - +0.1
396,099 - -0.7
396,460 + Rv0331 0.22 +0.1
396,461 - Rv0331 0.22 +0.0
396,461 - Rv0331 0.22 -0.1
396,512 - Rv0331 0.27 -0.6
396,585 + Rv0331 0.33 -0.1
396,872 - Rv0331 0.57 -1.1
397,010 - Rv0331 0.69 +0.1
397,038 - Rv0331 0.72 -0.2

Or see this region's nucleotide sequence