Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3889c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3888c and Rv3889c are separated by 93 nucleotidesRv3889c and Rv3890c are separated by 95 nucleotidesRv3890c and Rv3891c are separated by 35 nucleotidesRv3891c and Rv3892c are separated by 111 nucleotides Rv3888c: Rv3888c - Probable conserved membrane protein, at 4,371,681 to 4,372,706 Rv3888c Rv3889c: Rv3889c - ESX-2 secretion-associated protein EspG2, at 4,372,800 to 4,373,630 Rv3889c Rv3890c: Rv3890c - ESAT-6 like protein EsxC (ESAT-6 like protein 11), at 4,373,726 to 4,374,013 Rv3890c Rv3891c: Rv3891c - Possible ESAT-6 like protein EsxD, at 4,374,049 to 4,374,372 Rv3891c Rv3892c: Rv3892c - PPE family protein PPE69, at 4,374,484 to 4,375,683 Rv3892c Position (kb) 4372 4373 4374Strain fitness (log2 ratio) -2 -1 0 1 2at 4371.868 kb on + strand, within Rv3888cat 4371.961 kb on + strand, within Rv3888cat 4371.961 kb on + strand, within Rv3888cat 4371.962 kb on - strand, within Rv3888cat 4372.097 kb on + strand, within Rv3888cat 4372.260 kb on - strand, within Rv3888cat 4372.718 kb on + strandat 4372.823 kb on - strandat 4372.823 kb on - strandat 4373.091 kb on + strand, within Rv3889cat 4373.091 kb on + strand, within Rv3889cat 4373.091 kb on + strand, within Rv3889cat 4373.092 kb on - strand, within Rv3889cat 4373.125 kb on + strand, within Rv3889cat 4373.151 kb on + strand, within Rv3889cat 4373.160 kb on + strand, within Rv3889cat 4373.160 kb on + strand, within Rv3889cat 4373.161 kb on - strand, within Rv3889cat 4373.163 kb on + strand, within Rv3889cat 4373.163 kb on + strand, within Rv3889cat 4373.164 kb on - strand, within Rv3889cat 4373.164 kb on - strand, within Rv3889cat 4373.164 kb on - strand, within Rv3889cat 4373.164 kb on - strand, within Rv3889cat 4373.287 kb on + strand, within Rv3889cat 4373.395 kb on - strand, within Rv3889cat 4373.551 kb on - strandat 4373.595 kb on + strandat 4373.595 kb on + strandat 4373.595 kb on + strandat 4373.596 kb on - strandat 4373.599 kb on - strandat 4373.652 kb on + strandat 4373.652 kb on + strandat 4373.652 kb on + strandat 4373.695 kb on + strandat 4373.727 kb on + strandat 4373.728 kb on - strandat 4373.788 kb on + strand, within Rv3890cat 4373.789 kb on - strand, within Rv3890cat 4373.789 kb on - strand, within Rv3890cat 4373.925 kb on + strand, within Rv3890cat 4373.925 kb on + strand, within Rv3890cat 4373.926 kb on - strand, within Rv3890cat 4373.969 kb on + strand, within Rv3890cat 4373.993 kb on - strandat 4373.994 kb on + strandat 4373.994 kb on + strandat 4373.994 kb on + strandat 4373.995 kb on - strandat 4373.995 kb on - strandat 4374.208 kb on - strand, within Rv3891cat 4374.208 kb on - strand, within Rv3891cat 4374.272 kb on - strand, within Rv3891cat 4374.272 kb on - strand, within Rv3891cat 4374.276 kb on - strand, within Rv3891cat 4374.414 kb on + strandat 4374.436 kb on + strandat 4374.436 kb on + strandat 4374.437 kb on - strandat 4374.437 kb on - strandat 4374.437 kb on - strandat 4374.437 kb on - strandat 4374.479 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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4,371,868 + Rv3888c 0.18 -0.8
4,371,961 + Rv3888c 0.27 -0.3
4,371,961 + Rv3888c 0.27 -0.2
4,371,962 - Rv3888c 0.27 -0.5
4,372,097 + Rv3888c 0.41 -0.5
4,372,260 - Rv3888c 0.56 -0.5
4,372,718 + +0.3
4,372,823 - -0.2
4,372,823 - +0.3
4,373,091 + Rv3889c 0.35 -0.3
4,373,091 + Rv3889c 0.35 -1.3
4,373,091 + Rv3889c 0.35 -0.1
4,373,092 - Rv3889c 0.35 -0.2
4,373,125 + Rv3889c 0.39 -0.2
4,373,151 + Rv3889c 0.42 -0.3
4,373,160 + Rv3889c 0.43 -0.5
4,373,160 + Rv3889c 0.43 -0.9
4,373,161 - Rv3889c 0.43 -0.2
4,373,163 + Rv3889c 0.44 -0.1
4,373,163 + Rv3889c 0.44 -0.9
4,373,164 - Rv3889c 0.44 -0.6
4,373,164 - Rv3889c 0.44 -0.0
4,373,164 - Rv3889c 0.44 -0.2
4,373,164 - Rv3889c 0.44 -0.3
4,373,287 + Rv3889c 0.59 -0.1
4,373,395 - Rv3889c 0.72 +0.0
4,373,551 - -0.1
4,373,595 + -0.1
4,373,595 + +0.2
4,373,595 + -0.2
4,373,596 - +0.1
4,373,599 - +0.1
4,373,652 + -0.7
4,373,652 + -0.8
4,373,652 + -1.6
4,373,695 + +0.1
4,373,727 + +0.2
4,373,728 - -0.3
4,373,788 + Rv3890c 0.22 +0.2
4,373,789 - Rv3890c 0.22 -0.4
4,373,789 - Rv3890c 0.22 -0.1
4,373,925 + Rv3890c 0.69 -0.0
4,373,925 + Rv3890c 0.69 -0.5
4,373,926 - Rv3890c 0.69 +0.1
4,373,969 + Rv3890c 0.84 +0.8
4,373,993 - +0.3
4,373,994 + -0.5
4,373,994 + -1.9
4,373,994 + +0.2
4,373,995 - -1.0
4,373,995 - +0.0
4,374,208 - Rv3891c 0.49 +0.3
4,374,208 - Rv3891c 0.49 -1.0
4,374,272 - Rv3891c 0.69 -0.7
4,374,272 - Rv3891c 0.69 -0.7
4,374,276 - Rv3891c 0.70 -0.4
4,374,414 + +1.8
4,374,436 + +1.0
4,374,436 + +0.1
4,374,437 - -0.6
4,374,437 - -0.4
4,374,437 - +0.2
4,374,437 - +0.3
4,374,479 + -0.3

Or see this region's nucleotide sequence