Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3516

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3515c and Rv3516 are separated by 73 nucleotidesRv3516 and Rv3517 are separated by 95 nucleotidesRv3517 and Rv3518c are separated by 54 nucleotides Rv3515c: Rv3515c - Fatty-acid-CoA ligase FadD19 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 3,950,824 to 3,952,470 Rv3515c Rv3516: Rv3516 - Possible enoyl-CoA hydratase EchA19 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 3,952,544 to 3,953,335 Rv3516 Rv3517: Rv3517 - Conserved hypothetical protein, at 3,953,431 to 3,954,270 Rv3517 Rv3518c: Rv3518c - Probable cytochrome P450 monooxygenase 142 Cyp142, at 3,954,325 to 3,955,521 Rv3518c Position (kb) 3952 3953 3954Strain fitness (log2 ratio) -1 0 1 2 3at 3951.839 kb on + strand, within Rv3515cat 3951.840 kb on - strand, within Rv3515cat 3951.953 kb on + strand, within Rv3515cat 3951.953 kb on + strand, within Rv3515cat 3951.962 kb on + strand, within Rv3515cat 3951.962 kb on + strand, within Rv3515cat 3951.962 kb on + strand, within Rv3515cat 3951.963 kb on - strand, within Rv3515cat 3951.963 kb on - strand, within Rv3515cat 3952.093 kb on + strand, within Rv3515cat 3952.093 kb on + strand, within Rv3515cat 3952.093 kb on + strand, within Rv3515cat 3952.094 kb on - strand, within Rv3515cat 3952.094 kb on - strand, within Rv3515cat 3952.185 kb on - strand, within Rv3515cat 3952.290 kb on - strand, within Rv3515cat 3952.290 kb on - strand, within Rv3515cat 3952.356 kb on + strandat 3952.374 kb on - strandat 3952.453 kb on - strandat 3952.453 kb on - strandat 3952.797 kb on - strand, within Rv3516at 3953.130 kb on + strand, within Rv3516at 3953.503 kb on + strandat 3953.504 kb on - strandat 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.527 kb on + strand, within Rv3517at 3953.528 kb on - strand, within Rv3517at 3953.583 kb on - strand, within Rv3517at 3953.677 kb on + strand, within Rv3517at 3953.678 kb on - strand, within Rv3517at 3953.678 kb on - strand, within Rv3517at 3953.763 kb on + strand, within Rv3517at 3953.764 kb on - strand, within Rv3517at 3953.928 kb on + strand, within Rv3517at 3954.046 kb on + strand, within Rv3517

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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3,951,839 + Rv3515c 0.62 +0.6
3,951,840 - Rv3515c 0.62 -0.8
3,951,953 + Rv3515c 0.69 -0.1
3,951,953 + Rv3515c 0.69 -1.5
3,951,962 + Rv3515c 0.69 +0.5
3,951,962 + Rv3515c 0.69 +1.2
3,951,962 + Rv3515c 0.69 -0.3
3,951,963 - Rv3515c 0.69 +0.1
3,951,963 - Rv3515c 0.69 -0.2
3,952,093 + Rv3515c 0.77 +0.0
3,952,093 + Rv3515c 0.77 -0.4
3,952,093 + Rv3515c 0.77 -0.6
3,952,094 - Rv3515c 0.77 -0.1
3,952,094 - Rv3515c 0.77 -0.3
3,952,185 - Rv3515c 0.83 -0.4
3,952,290 - Rv3515c 0.89 -0.0
3,952,290 - Rv3515c 0.89 -1.6
3,952,356 + +0.1
3,952,374 - +0.5
3,952,453 - -0.3
3,952,453 - -0.2
3,952,797 - Rv3516 0.32 -1.3
3,953,130 + Rv3516 0.74 -0.4
3,953,503 + -0.6
3,953,504 - -0.5
3,953,527 + Rv3517 0.11 -1.4
3,953,527 + Rv3517 0.11 -0.1
3,953,527 + Rv3517 0.11 -0.3
3,953,527 + Rv3517 0.11 +3.3
3,953,527 + Rv3517 0.11 +0.5
3,953,527 + Rv3517 0.11 +0.3
3,953,527 + Rv3517 0.11 +0.6
3,953,527 + Rv3517 0.11 -0.1
3,953,528 - Rv3517 0.12 -0.5
3,953,583 - Rv3517 0.18 +0.1
3,953,677 + Rv3517 0.29 -1.4
3,953,678 - Rv3517 0.29 +0.3
3,953,678 - Rv3517 0.29 -1.0
3,953,763 + Rv3517 0.40 +0.1
3,953,764 - Rv3517 0.40 +0.2
3,953,928 + Rv3517 0.59 +0.3
3,954,046 + Rv3517 0.73 +1.1

Or see this region's nucleotide sequence