Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0099

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0097 and Rv0098 overlap by 4 nucleotidesRv0098 and Rv0099 are separated by 4 nucleotidesRv0099 and Rv0100 are separated by 4 nucleotidesRv0100 and Rv0101 overlap by 19 nucleotides Rv0097: Rv0097 - Possible oxidoreductase, at 106,734 to 107,603 Rv0097 Rv0098: Rv0098 - Probable fatty acyl CoA thioesterase type III FcoT, at 107,600 to 108,151 Rv0098 Rv0099: Rv0099 - Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 108,156 to 109,778 Rv0099 Rv0100: Rv0100 - Conserved hypothetical protein, at 109,783 to 110,019 Rv0100 Rv0101: Rv0101 - Probable peptide synthetase Nrp (peptide synthase), at 110,001 to 117,539 Rv0101 Position (kb) 108 109 110Strain fitness (log2 ratio) -1 0 1 2at 107.245 kb on + strand, within Rv0097at 107.245 kb on + strand, within Rv0097at 107.245 kb on + strand, within Rv0097at 107.246 kb on - strand, within Rv0097at 107.246 kb on - strand, within Rv0097at 107.329 kb on - strand, within Rv0097at 107.452 kb on + strand, within Rv0097at 107.452 kb on + strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.453 kb on - strand, within Rv0097at 107.456 kb on + strand, within Rv0097at 107.457 kb on - strand, within Rv0097at 107.457 kb on - strand, within Rv0097at 107.797 kb on + strand, within Rv0098at 107.927 kb on + strand, within Rv0098at 107.947 kb on + strand, within Rv0098at 108.356 kb on + strand, within Rv0099at 108.393 kb on + strand, within Rv0099at 108.807 kb on + strand, within Rv0099at 108.854 kb on + strand, within Rv0099at 108.854 kb on + strand, within Rv0099at 108.855 kb on - strand, within Rv0099at 109.286 kb on - strand, within Rv0099at 109.286 kb on - strand, within Rv0099at 109.822 kb on + strand, within Rv0100at 109.916 kb on + strand, within Rv0100at 109.917 kb on - strand, within Rv0100at 110.041 kb on - strandat 110.075 kb on - strandat 110.075 kb on - strandat 110.149 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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107,245 + Rv0097 0.59 -0.3
107,245 + Rv0097 0.59 -0.1
107,245 + Rv0097 0.59 +0.6
107,246 - Rv0097 0.59 -0.4
107,246 - Rv0097 0.59 +0.1
107,329 - Rv0097 0.68 -0.3
107,452 + Rv0097 0.83 -0.3
107,452 + Rv0097 0.83 +0.2
107,453 - Rv0097 0.83 -0.7
107,453 - Rv0097 0.83 -0.3
107,453 - Rv0097 0.83 -0.3
107,453 - Rv0097 0.83 -0.2
107,453 - Rv0097 0.83 +0.4
107,453 - Rv0097 0.83 +0.1
107,453 - Rv0097 0.83 -0.0
107,456 + Rv0097 0.83 -1.1
107,457 - Rv0097 0.83 -0.2
107,457 - Rv0097 0.83 -0.1
107,797 + Rv0098 0.36 -0.3
107,927 + Rv0098 0.59 -0.1
107,947 + Rv0098 0.63 -1.1
108,356 + Rv0099 0.12 -0.0
108,393 + Rv0099 0.15 -0.6
108,807 + Rv0099 0.40 +2.3
108,854 + Rv0099 0.43 +0.4
108,854 + Rv0099 0.43 +0.1
108,855 - Rv0099 0.43 +0.2
109,286 - Rv0099 0.70 +0.5
109,286 - Rv0099 0.70 -1.2
109,822 + Rv0100 0.16 -0.4
109,916 + Rv0100 0.56 +0.7
109,917 - Rv0100 0.57 +0.1
110,041 - -0.1
110,075 - -0.8
110,075 - -0.2
110,149 + -0.8

Or see this region's nucleotide sequence