Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3667

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3666c and Rv3667 are separated by 707 nucleotidesRv3667 and Rv3668c are separated by 35 nucleotides Rv3666c: Rv3666c - Probable periplasmic dipeptide-binding lipoprotein DppA, at 4,105,459 to 4,107,084 Rv3666c Rv3667: Rv3667 - Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase), at 4,107,792 to 4,109,747 Rv3667 Rv3668c: Rv3668c - Possible protease, at 4,109,783 to 4,110,481 Rv3668c Position (kb) 4107 4108 4109 4110Strain fitness (log2 ratio) -3 -2 -1 0 1at 4106.876 kb on + strand, within Rv3666cat 4107.438 kb on + strandat 4107.439 kb on - strandat 4107.530 kb on + strandat 4107.667 kb on + strandat 4107.695 kb on + strandat 4107.765 kb on + strandat 4107.765 kb on + strandat 4108.116 kb on + strand, within Rv3667at 4108.117 kb on - strand, within Rv3667at 4108.138 kb on + strand, within Rv3667at 4108.200 kb on + strand, within Rv3667at 4108.201 kb on - strand, within Rv3667at 4108.265 kb on + strand, within Rv3667at 4108.266 kb on - strand, within Rv3667at 4108.576 kb on - strand, within Rv3667at 4108.610 kb on + strand, within Rv3667at 4108.647 kb on + strand, within Rv3667at 4108.647 kb on + strand, within Rv3667at 4108.734 kb on + strand, within Rv3667at 4109.196 kb on + strand, within Rv3667at 4109.299 kb on - strand, within Rv3667at 4109.299 kb on - strand, within Rv3667at 4109.326 kb on + strand, within Rv3667at 4109.350 kb on + strand, within Rv3667at 4109.353 kb on + strand, within Rv3667at 4109.510 kb on - strand, within Rv3667at 4109.520 kb on + strand, within Rv3667at 4109.520 kb on + strand, within Rv3667at 4109.521 kb on - strand, within Rv3667at 4109.521 kb on - strand, within Rv3667at 4109.608 kb on + strandat 4109.621 kb on - strandat 4109.793 kb on - strandat 4109.889 kb on + strand, within Rv3668cat 4109.890 kb on - strand, within Rv3668cat 4110.040 kb on + strand, within Rv3668cat 4110.184 kb on - strand, within Rv3668cat 4110.184 kb on - strand, within Rv3668cat 4110.330 kb on - strand, within Rv3668cat 4110.384 kb on - strand, within Rv3668cat 4110.384 kb on - strand, within Rv3668c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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4,106,876 + Rv3666c 0.87 +0.6
4,107,438 + -1.0
4,107,439 - -0.2
4,107,530 + +1.7
4,107,667 + +0.4
4,107,695 + +0.3
4,107,765 + +0.4
4,107,765 + -0.7
4,108,116 + Rv3667 0.17 -1.6
4,108,117 - Rv3667 0.17 +0.7
4,108,138 + Rv3667 0.18 -2.8
4,108,200 + Rv3667 0.21 -0.5
4,108,201 - Rv3667 0.21 -1.3
4,108,265 + Rv3667 0.24 -0.8
4,108,266 - Rv3667 0.24 -1.0
4,108,576 - Rv3667 0.40 -0.2
4,108,610 + Rv3667 0.42 -0.5
4,108,647 + Rv3667 0.44 -1.4
4,108,647 + Rv3667 0.44 -0.7
4,108,734 + Rv3667 0.48 -0.0
4,109,196 + Rv3667 0.72 -2.1
4,109,299 - Rv3667 0.77 -1.4
4,109,299 - Rv3667 0.77 -0.1
4,109,326 + Rv3667 0.78 +1.7
4,109,350 + Rv3667 0.80 +0.7
4,109,353 + Rv3667 0.80 +0.2
4,109,510 - Rv3667 0.88 -0.6
4,109,520 + Rv3667 0.88 -1.2
4,109,520 + Rv3667 0.88 -0.4
4,109,521 - Rv3667 0.88 -1.0
4,109,521 - Rv3667 0.88 -0.5
4,109,608 + -0.1
4,109,621 - -0.2
4,109,793 - -0.5
4,109,889 + Rv3668c 0.15 -0.2
4,109,890 - Rv3668c 0.15 -0.9
4,110,040 + Rv3668c 0.37 -0.0
4,110,184 - Rv3668c 0.57 +0.9
4,110,184 - Rv3668c 0.57 -0.1
4,110,330 - Rv3668c 0.78 -0.0
4,110,384 - Rv3668c 0.86 +1.0
4,110,384 - Rv3668c 0.86 -0.9

Or see this region's nucleotide sequence