Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3600c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3598c and Rv3599c are separated by 11 nucleotidesRv3599c and Rv3600c are separated by 5 nucleotidesRv3600c and Rv3601c are separated by 2 nucleotidesRv3601c and Rv3602c overlap by 1 nucleotides Rv3598c: Rv3598c - Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase), at 4,041,423 to 4,042,940 Rv3598c Rv3599c: Rv3599c - Hypothetical short protein, at 4,042,952 to 4,043,035 Rv3599c Rv3600c: Rv3600c - Conserved protein, at 4,043,041 to 4,043,859 Rv3600c Rv3601c: Rv3601c - Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase), at 4,043,862 to 4,044,281 Rv3601c Rv3602c: Rv3602c - Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme), at 4,044,281 to 4,045,210 Rv3602c Position (kb) 4043 4044Strain fitness (log2 ratio) -3 -2 -1 0 1at 4042.953 kb on + strandat 4042.953 kb on + strandat 4042.954 kb on - strandat 4043.242 kb on + strand, within Rv3600cat 4043.243 kb on - strand, within Rv3600cat 4043.243 kb on - strand, within Rv3600cat 4043.243 kb on - strand, within Rv3600cat 4043.437 kb on + strand, within Rv3600cat 4043.501 kb on + strand, within Rv3600cat 4043.619 kb on - strand, within Rv3600c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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4,042,953 + +0.3
4,042,953 + -1.1
4,042,954 - +1.0
4,043,242 + Rv3600c 0.25 -2.9
4,043,243 - Rv3600c 0.25 -0.6
4,043,243 - Rv3600c 0.25 -0.7
4,043,243 - Rv3600c 0.25 -0.5
4,043,437 + Rv3600c 0.48 -0.9
4,043,501 + Rv3600c 0.56 +0.8
4,043,619 - Rv3600c 0.71 +0.0

Or see this region's nucleotide sequence