Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3177

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3176c and Rv3177 are separated by 146 nucleotidesRv3177 and Rv3178 are separated by 130 nucleotides Rv3176c: Rv3176c - Probable epoxide hydrolase MesT (epoxide hydratase) (arene-oxide hydratase), at 3,544,344 to 3,545,300 Rv3176c Rv3177: Rv3177 - Possible peroxidase (non-haem peroxidase), at 3,545,447 to 3,546,307 Rv3177 Rv3178: Rv3178 - Conserved hypothetical protein, at 3,546,438 to 3,546,797 Rv3178 Position (kb) 3545 3546 3547Strain fitness (log2 ratio) -1 0 1at 3544.927 kb on + strand, within Rv3176cat 3545.017 kb on + strand, within Rv3176cat 3545.054 kb on - strand, within Rv3176cat 3545.063 kb on - strand, within Rv3176cat 3545.119 kb on + strand, within Rv3176cat 3545.119 kb on + strand, within Rv3176cat 3545.181 kb on + strand, within Rv3176cat 3545.181 kb on + strand, within Rv3176cat 3545.181 kb on + strand, within Rv3176cat 3545.392 kb on + strandat 3545.401 kb on + strandat 3545.401 kb on + strandat 3545.484 kb on - strandat 3545.534 kb on + strand, within Rv3177at 3546.406 kb on - strandat 3546.535 kb on - strand, within Rv3178at 3546.548 kb on + strand, within Rv3178at 3546.719 kb on - strand, within Rv3178at 3546.906 kb on - strandat 3547.105 kb on - strandat 3547.130 kb on + strandat 3547.131 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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3,544,927 + Rv3176c 0.61 +0.1
3,545,017 + Rv3176c 0.70 -0.1
3,545,054 - Rv3176c 0.74 +1.3
3,545,063 - Rv3176c 0.75 +0.3
3,545,119 + Rv3176c 0.81 +0.9
3,545,119 + Rv3176c 0.81 -1.5
3,545,181 + Rv3176c 0.87 -0.4
3,545,181 + Rv3176c 0.87 +0.3
3,545,181 + Rv3176c 0.87 +1.7
3,545,392 + +0.2
3,545,401 + +0.0
3,545,401 + +1.7
3,545,484 - +0.4
3,545,534 + Rv3177 0.10 -1.0
3,546,406 - +1.1
3,546,535 - Rv3178 0.27 -0.3
3,546,548 + Rv3178 0.31 -0.3
3,546,719 - Rv3178 0.78 -0.0
3,546,906 - -0.3
3,547,105 - +1.2
3,547,130 + -0.5
3,547,131 - +0.5

Or see this region's nucleotide sequence