Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3171c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3170 and Rv3171c overlap by 6 nucleotidesRv3171c and Rv3172c are separated by 136 nucleotidesRv3172c and Rv3173c are separated by 78 nucleotides Rv3170: Rv3170 - Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO), at 3,538,505 to 3,539,851 Rv3170 Rv3171c: Rv3171c - Possible non-heme haloperoxidase Hpx, at 3,539,846 to 3,540,745 Rv3171c Rv3172c: Rv3172c - Hypothetical protein, at 3,540,882 to 3,541,364 Rv3172c Rv3173c: Rv3173c - Probable transcriptional regulatory protein (probably TetR/AcrR-family), at 3,541,443 to 3,542,045 Rv3173c Position (kb) 3539 3540 3541Strain fitness (log2 ratio) -1 0 1at 3539.070 kb on - strand, within Rv3170at 3539.073 kb on + strand, within Rv3170at 3539.073 kb on + strand, within Rv3170at 3539.074 kb on - strand, within Rv3170at 3539.789 kb on + strandat 3539.847 kb on + strandat 3540.036 kb on - strand, within Rv3171cat 3540.540 kb on + strand, within Rv3171cat 3540.762 kb on - strandat 3540.915 kb on - strandat 3540.915 kb on - strandat 3540.980 kb on + strand, within Rv3172cat 3540.980 kb on + strand, within Rv3172cat 3541.081 kb on + strand, within Rv3172cat 3541.081 kb on + strand, within Rv3172cat 3541.081 kb on + strand, within Rv3172cat 3541.082 kb on - strand, within Rv3172cat 3541.162 kb on - strand, within Rv3172cat 3541.268 kb on - strand, within Rv3172cat 3541.268 kb on - strand, within Rv3172cat 3541.289 kb on - strand, within Rv3172cat 3541.291 kb on + strand, within Rv3172cat 3541.291 kb on + strand, within Rv3172cat 3541.291 kb on + strand, within Rv3172cat 3541.375 kb on + strandat 3541.375 kb on + strandat 3541.634 kb on - strand, within Rv3173c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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3,539,070 - Rv3170 0.42 +0.2
3,539,073 + Rv3170 0.42 -0.1
3,539,073 + Rv3170 0.42 -0.5
3,539,074 - Rv3170 0.42 -0.1
3,539,789 + -0.3
3,539,847 + +0.4
3,540,036 - Rv3171c 0.21 +0.5
3,540,540 + Rv3171c 0.77 +1.0
3,540,762 - -0.4
3,540,915 - -0.2
3,540,915 - -0.2
3,540,980 + Rv3172c 0.20 -0.9
3,540,980 + Rv3172c 0.20 -0.0
3,541,081 + Rv3172c 0.41 -0.4
3,541,081 + Rv3172c 0.41 -0.9
3,541,081 + Rv3172c 0.41 -0.1
3,541,082 - Rv3172c 0.41 -0.1
3,541,162 - Rv3172c 0.58 -0.2
3,541,268 - Rv3172c 0.80 +0.0
3,541,268 - Rv3172c 0.80 -0.1
3,541,289 - Rv3172c 0.84 -0.1
3,541,291 + Rv3172c 0.85 +0.8
3,541,291 + Rv3172c 0.85 -0.1
3,541,291 + Rv3172c 0.85 +0.0
3,541,375 + -0.1
3,541,375 + -0.2
3,541,634 - Rv3173c 0.32 -0.5

Or see this region's nucleotide sequence