Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2993c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2992c and Rv2993c overlap by 4 nucleotidesRv2993c and Rv2994 are separated by 275 nucleotides Rv2992c: Rv2992c - Glutamyl-tRNA synthetase GltS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS), at 3,348,805 to 3,350,277 Rv2992c Rv2993c: Rv2993c - Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase), at 3,350,274 to 3,350,993 Rv2993c Rv2994: Rv2994 - Probable conserved integral membrane protein, at 3,351,269 to 3,352,606 Rv2994 Position (kb) 3350 3351Strain fitness (log2 ratio) -2 -1 0 1at 3350.416 kb on - strand, within Rv2993cat 3350.664 kb on - strand, within Rv2993cat 3350.664 kb on - strand, within Rv2993cat 3351.409 kb on - strand, within Rv2994at 3351.545 kb on + strand, within Rv2994at 3351.916 kb on - strand, within Rv2994

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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3,350,416 - Rv2993c 0.20 -0.4
3,350,664 - Rv2993c 0.54 -1.7
3,350,664 - Rv2993c 0.54 -2.3
3,351,409 - Rv2994 0.10 -0.6
3,351,545 + Rv2994 0.21 -0.5
3,351,916 - Rv2994 0.48 -0.9

Or see this region's nucleotide sequence