Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2522c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2519 and Rv2520c are separated by 124 nucleotidesRv2520c and Rv2521 are separated by 68 nucleotidesRv2521 and Rv2522c overlap by 29 nucleotidesRv2522c and Rv2523c overlap by 4 nucleotidesRv2523c and Rv2524c are separated by 192 nucleotides Rv2519: Rv2519 - PE family protein PE26, at 2,835,785 to 2,837,263 Rv2519 Rv2520c: Rv2520c - Possible conserved membrane protein, at 2,837,388 to 2,837,615 Rv2520c Rv2521: Rv2521 - Probable bacterioferritin comigratory protein Bcp, at 2,837,684 to 2,838,157 Rv2521 Rv2522c: Rv2522c - Conserved hypothetical protein, at 2,838,129 to 2,839,541 Rv2522c Rv2523c: Rv2523c - holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase), at 2,839,538 to 2,839,930 Rv2523c Rv2524c: Rv2524c - Probable fatty acid synthase Fas (fatty acid synthetase), at 2,840,123 to 2,849,332 Rv2524c Position (kb) 2838 2839 2840Strain fitness (log2 ratio) -1 0 1 2at 2837.179 kb on - strandat 2837.202 kb on + strandat 2837.204 kb on + strandat 2837.205 kb on - strandat 2837.206 kb on + strandat 2837.206 kb on + strandat 2837.206 kb on + strandat 2837.206 kb on + strandat 2837.207 kb on - strandat 2837.262 kb on - strandat 2837.262 kb on - strandat 2837.326 kb on - strandat 2837.673 kb on - strandat 2837.677 kb on + strandat 2837.775 kb on - strand, within Rv2521at 2837.799 kb on - strand, within Rv2521at 2837.804 kb on + strand, within Rv2521at 2837.929 kb on + strand, within Rv2521at 2838.026 kb on + strand, within Rv2521at 2838.027 kb on - strand, within Rv2521at 2838.131 kb on - strandat 2838.154 kb on - strandat 2838.155 kb on + strandat 2838.261 kb on + strandat 2838.394 kb on + strand, within Rv2522cat 2838.421 kb on + strand, within Rv2522cat 2838.543 kb on - strand, within Rv2522cat 2838.543 kb on - strand, within Rv2522cat 2838.615 kb on + strand, within Rv2522cat 2839.144 kb on + strand, within Rv2522cat 2839.144 kb on + strand, within Rv2522cat 2839.231 kb on + strand, within Rv2522cat 2839.232 kb on - strand, within Rv2522cat 2839.944 kb on - strandat 2840.059 kb on - strandat 2840.059 kb on - strandat 2840.134 kb on - strandat 2840.134 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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2,837,179 - +0.6
2,837,202 + -0.4
2,837,204 + -0.9
2,837,205 - -0.6
2,837,206 + -0.2
2,837,206 + -0.0
2,837,206 + +0.1
2,837,206 + +0.6
2,837,207 - -0.6
2,837,262 - +1.7
2,837,262 - -0.0
2,837,326 - -1.0
2,837,673 - -0.2
2,837,677 + +0.1
2,837,775 - Rv2521 0.19 -0.0
2,837,799 - Rv2521 0.24 -0.4
2,837,804 + Rv2521 0.25 -0.7
2,837,929 + Rv2521 0.52 -0.1
2,838,026 + Rv2521 0.72 +0.5
2,838,027 - Rv2521 0.72 +1.0
2,838,131 - +0.9
2,838,154 - -0.4
2,838,155 + -0.5
2,838,261 + -0.2
2,838,394 + Rv2522c 0.19 -1.2
2,838,421 + Rv2522c 0.21 -0.8
2,838,543 - Rv2522c 0.29 +0.2
2,838,543 - Rv2522c 0.29 -0.5
2,838,615 + Rv2522c 0.34 -0.9
2,839,144 + Rv2522c 0.72 -0.4
2,839,144 + Rv2522c 0.72 -0.3
2,839,231 + Rv2522c 0.78 -0.7
2,839,232 - Rv2522c 0.78 -0.1
2,839,944 - +0.5
2,840,059 - +0.7
2,840,059 - +2.2
2,840,134 - -1.7
2,840,134 - -0.5

Or see this region's nucleotide sequence