Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2415c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2414c and Rv2415c are separated by 14 nucleotidesRv2415c and Rv2416c are separated by 339 nucleotides Rv2414c: Rv2414c - Conserved hypothetical protein, at 2,711,332 to 2,712,876 Rv2414c Rv2415c: Rv2415c - Conserved hypothetical protein, at 2,712,891 to 2,713,784 Rv2415c Rv2416c: Rv2416c - Enhanced intracellular survival protein Eis,GCN5-related N-acetyltransferase, at 2,714,124 to 2,715,332 Rv2416c Position (kb) 2712 2713 2714Strain fitness (log2 ratio) -3 -2 -1 0 1at 2712.305 kb on - strand, within Rv2414cat 2712.388 kb on - strand, within Rv2414cat 2712.848 kb on - strandat 2712.848 kb on - strandat 2712.977 kb on + strandat 2713.091 kb on + strand, within Rv2415cat 2713.091 kb on + strand, within Rv2415cat 2713.091 kb on + strand, within Rv2415cat 2713.103 kb on + strand, within Rv2415cat 2713.500 kb on + strand, within Rv2415cat 2713.699 kb on - strandat 2714.405 kb on - strand, within Rv2416cat 2714.471 kb on + strand, within Rv2416cat 2714.472 kb on - strand, within Rv2416cat 2714.666 kb on - strand, within Rv2416c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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2,712,305 - Rv2414c 0.63 -0.1
2,712,388 - Rv2414c 0.68 -0.5
2,712,848 - -0.2
2,712,848 - -0.5
2,712,977 + -0.1
2,713,091 + Rv2415c 0.22 -3.6
2,713,091 + Rv2415c 0.22 -0.5
2,713,091 + Rv2415c 0.22 -0.4
2,713,103 + Rv2415c 0.24 -1.0
2,713,500 + Rv2415c 0.68 -0.1
2,713,699 - +0.9
2,714,405 - Rv2416c 0.23 -0.3
2,714,471 + Rv2416c 0.29 -0.7
2,714,472 - Rv2416c 0.29 +0.6
2,714,666 - Rv2416c 0.45 -0.1

Or see this region's nucleotide sequence