Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2252

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2251 and Rv2252 overlap by 4 nucleotidesRv2252 and Rv2253 are separated by 65 nucleotidesRv2253 and Rv2254c are separated by 32 nucleotides Rv2251: Rv2251 - Possible flavoprotein, at 2,525,565 to 2,526,992 Rv2251 Rv2252: Rv2252 - Diacylglycerol kinase, at 2,526,989 to 2,527,918 Rv2252 Rv2253: Rv2253 - Possible secreted unknown protein, at 2,527,984 to 2,528,487 Rv2253 Rv2254c: Rv2254c - Probable integral membrane protein, at 2,528,520 to 2,528,975 Rv2254c Position (kb) 2526 2527 2528Strain fitness (log2 ratio) -1 0 1at 2526.250 kb on - strand, within Rv2251at 2526.250 kb on - strand, within Rv2251at 2526.562 kb on - strand, within Rv2251at 2527.632 kb on - strand, within Rv2252at 2527.830 kb on - strandat 2528.155 kb on + strand, within Rv2253at 2528.173 kb on + strand, within Rv2253at 2528.174 kb on - strand, within Rv2253at 2528.174 kb on - strand, within Rv2253at 2528.347 kb on + strand, within Rv2253at 2528.348 kb on - strand, within Rv2253at 2528.348 kb on - strand, within Rv2253at 2528.439 kb on + strandat 2528.440 kb on - strandat 2528.736 kb on + strand, within Rv2254cat 2528.750 kb on - strand, within Rv2254c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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2,526,250 - Rv2251 0.48 +0.1
2,526,250 - Rv2251 0.48 -1.0
2,526,562 - Rv2251 0.70 -1.0
2,527,632 - Rv2252 0.69 -0.6
2,527,830 - -0.6
2,528,155 + Rv2253 0.34 +0.0
2,528,173 + Rv2253 0.38 +1.4
2,528,174 - Rv2253 0.38 -0.0
2,528,174 - Rv2253 0.38 -0.9
2,528,347 + Rv2253 0.72 -0.2
2,528,348 - Rv2253 0.72 -0.3
2,528,348 - Rv2253 0.72 -0.9
2,528,439 + -0.6
2,528,440 - -0.5
2,528,736 + Rv2254c 0.47 +0.1
2,528,750 - Rv2254c 0.50 -0.4

Or see this region's nucleotide sequence