Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1449c

Experiment: D-Lactate 10 mM (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1448c and Rv1449c are separated by 16 nucleotidesRv1449c and Rv1450c are separated by 438 nucleotides Rv1448c: Rv1448c - Probable transaldolase Tal, at 1,626,959 to 1,628,080 Rv1448c Rv1449c: Rv1449c - Transketolase Tkt (TK), at 1,628,097 to 1,630,199 Rv1449c Rv1450c: Rv1450c - PE-PGRS family protein PE_PGRS27, at 1,630,638 to 1,634,627 Rv1450c Position (kb) 1628 1629 1630 1631Strain fitness (log2 ratio) -3 -2 -1 0 1at 1627.227 kb on + strand, within Rv1448cat 1627.228 kb on - strand, within Rv1448cat 1627.357 kb on - strand, within Rv1448cat 1627.854 kb on - strand, within Rv1448cat 1627.896 kb on + strand, within Rv1448cat 1628.034 kb on - strandat 1630.242 kb on - strandat 1630.242 kb on - strandat 1630.275 kb on - strandat 1630.306 kb on + strandat 1630.307 kb on - strandat 1630.393 kb on - strandat 1630.406 kb on + strandat 1630.407 kb on - strandat 1630.456 kb on + strandat 1630.457 kb on - strandat 1630.457 kb on - strandat 1630.640 kb on - strandat 1630.640 kb on - strandat 1630.700 kb on + strandat 1630.701 kb on - strandat 1630.701 kb on - strandat 1631.003 kb on + strandat 1631.004 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
remove
1,627,227 + Rv1448c 0.24 -0.6
1,627,228 - Rv1448c 0.24 +0.1
1,627,357 - Rv1448c 0.35 -0.4
1,627,854 - Rv1448c 0.80 -0.3
1,627,896 + Rv1448c 0.84 -1.8
1,628,034 - -0.1
1,630,242 - -1.4
1,630,242 - +0.3
1,630,275 - +1.7
1,630,306 + -0.8
1,630,307 - -0.1
1,630,393 - -0.9
1,630,406 + -2.9
1,630,407 - -1.5
1,630,456 + +0.8
1,630,457 - -0.3
1,630,457 - -0.1
1,630,640 - -0.9
1,630,640 - -0.8
1,630,700 + -0.7
1,630,701 - -0.5
1,630,701 - +0.1
1,631,003 + -0.1
1,631,004 - +1.7

Or see this region's nucleotide sequence