Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1251c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1250 and Rv1251c overlap by 98 nucleotidesRv1251c and Rv1252c are separated by 55 nucleotidesRv1252c and Rv1253 are separated by 65 nucleotides Rv1250: Rv1250 - Probable drug-transport integral membrane protein, at 1,394,179 to 1,395,918 Rv1250 Rv1251c: Rv1251c - Conserved hypothetical protein, at 1,395,821 to 1,399,240 Rv1251c Rv1252c: Rv1252c - Probable lipoprotein LprE, at 1,399,296 to 1,399,904 Rv1252c Rv1253: Rv1253 - Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog), at 1,399,970 to 1,401,661 Rv1253 Position (kb) 1395 1396 1397 1398 1399 1400Strain fitness (log2 ratio) -1 0 1at 1394.847 kb on - strand, within Rv1250at 1395.064 kb on + strand, within Rv1250at 1395.065 kb on - strand, within Rv1250at 1395.602 kb on + strand, within Rv1250at 1395.703 kb on + strand, within Rv1250at 1395.713 kb on - strand, within Rv1250at 1395.889 kb on - strandat 1395.914 kb on + strandat 1395.914 kb on + strandat 1395.927 kb on + strandat 1396.071 kb on - strandat 1396.076 kb on + strandat 1396.144 kb on - strandat 1396.298 kb on - strand, within Rv1251cat 1396.372 kb on - strand, within Rv1251cat 1396.417 kb on - strand, within Rv1251cat 1396.428 kb on - strand, within Rv1251cat 1396.523 kb on + strand, within Rv1251cat 1396.729 kb on - strand, within Rv1251cat 1396.921 kb on - strand, within Rv1251cat 1397.072 kb on + strand, within Rv1251cat 1397.337 kb on + strand, within Rv1251cat 1398.099 kb on + strand, within Rv1251cat 1398.543 kb on - strand, within Rv1251cat 1398.810 kb on - strand, within Rv1251cat 1398.930 kb on + strandat 1399.174 kb on - strandat 1399.212 kb on + strandat 1399.213 kb on - strandat 1399.384 kb on + strand, within Rv1252cat 1399.445 kb on + strand, within Rv1252cat 1399.468 kb on + strand, within Rv1252cat 1399.469 kb on - strand, within Rv1252cat 1399.564 kb on + strand, within Rv1252cat 1399.793 kb on + strand, within Rv1252cat 1399.908 kb on - strandat 1399.985 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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1,394,847 - Rv1250 0.38 -0.2
1,395,064 + Rv1250 0.51 +0.1
1,395,065 - Rv1250 0.51 -0.0
1,395,602 + Rv1250 0.82 +0.3
1,395,703 + Rv1250 0.88 +0.3
1,395,713 - Rv1250 0.88 -0.1
1,395,889 - -0.4
1,395,914 + +0.4
1,395,914 + -0.2
1,395,927 + +0.3
1,396,071 - -0.2
1,396,076 + -0.3
1,396,144 - -0.6
1,396,298 - Rv1251c 0.14 -0.5
1,396,372 - Rv1251c 0.16 +0.1
1,396,417 - Rv1251c 0.17 -0.6
1,396,428 - Rv1251c 0.18 -0.2
1,396,523 + Rv1251c 0.21 -1.0
1,396,729 - Rv1251c 0.27 -0.4
1,396,921 - Rv1251c 0.32 -0.2
1,397,072 + Rv1251c 0.37 -0.6
1,397,337 + Rv1251c 0.44 -1.1
1,398,099 + Rv1251c 0.67 -0.9
1,398,543 - Rv1251c 0.80 -1.5
1,398,810 - Rv1251c 0.87 -0.4
1,398,930 + +0.4
1,399,174 - -0.2
1,399,212 + +0.2
1,399,213 - -0.8
1,399,384 + Rv1252c 0.14 -0.7
1,399,445 + Rv1252c 0.24 -0.3
1,399,468 + Rv1252c 0.28 +0.4
1,399,469 - Rv1252c 0.28 -0.2
1,399,564 + Rv1252c 0.44 +0.2
1,399,793 + Rv1252c 0.82 -0.2
1,399,908 - -0.1
1,399,985 + -1.2

Or see this region's nucleotide sequence