Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0523c

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0522 and Rv0523c overlap by 17 nucleotidesRv0523c and Rv0524 are separated by 113 nucleotides Rv0522: Rv0522 - Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease), at 613,038 to 614,342 Rv0522 Rv0523c: Rv0523c - Conserved protein, at 614,326 to 614,721 Rv0523c Rv0524: Rv0524 - Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at), at 614,835 to 616,223 Rv0524 Position (kb) 614 615Strain fitness (log2 ratio) -2 -1 0 1at 613.328 kb on - strand, within Rv0522at 613.627 kb on + strand, within Rv0522at 613.785 kb on + strand, within Rv0522at 613.811 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.884 kb on + strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 613.885 kb on - strand, within Rv0522at 614.156 kb on - strand, within Rv0522at 614.295 kb on + strandat 614.296 kb on - strandat 614.296 kb on - strandat 614.348 kb on - strandat 614.402 kb on + strand, within Rv0523cat 614.403 kb on - strand, within Rv0523cat 614.684 kb on + strandat 614.685 kb on - strandat 614.685 kb on - strandat 614.713 kb on + strandat 614.827 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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613,328 - Rv0522 0.22 -0.3
613,627 + Rv0522 0.45 +1.0
613,785 + Rv0522 0.57 -0.7
613,811 + Rv0522 0.59 -1.4
613,884 + Rv0522 0.65 -0.6
613,884 + Rv0522 0.65 -0.1
613,884 + Rv0522 0.65 -0.1
613,884 + Rv0522 0.65 +0.3
613,885 - Rv0522 0.65 -1.2
613,885 - Rv0522 0.65 -0.1
613,885 - Rv0522 0.65 -0.1
613,885 - Rv0522 0.65 -0.3
613,885 - Rv0522 0.65 +0.1
614,156 - Rv0522 0.86 +0.8
614,295 + -1.1
614,296 - +0.2
614,296 - -0.1
614,348 - +0.0
614,402 + Rv0523c 0.19 -2.1
614,403 - Rv0523c 0.19 -0.4
614,684 + +0.7
614,685 - -0.3
614,685 - -0.2
614,713 + -0.2
614,827 + +0.4

Or see this region's nucleotide sequence