Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0508

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0507 and Rv0508 overlap by 8 nucleotidesRv0508 and Rv0509 are separated by 49 nucleotides Rv0507: Rv0507 - Probable conserved transmembrane transport protein MmpL2, at 597,199 to 600,105 Rv0507 Rv0508: Rv0508 - Conserved hypothetical protein, at 600,098 to 600,391 Rv0508 Rv0509: Rv0509 - Probable glutamyl-tRNA reductase HemA (GLUTR), at 600,441 to 601,847 Rv0509 Position (kb) 600 601Strain fitness (log2 ratio) -1 0 1at 599.124 kb on + strand, within Rv0507at 599.125 kb on - strand, within Rv0507at 599.392 kb on - strand, within Rv0507at 599.403 kb on - strand, within Rv0507at 599.434 kb on + strand, within Rv0507at 599.434 kb on + strand, within Rv0507at 599.776 kb on - strand, within Rv0507at 599.871 kb on + strandat 599.872 kb on - strandat 599.872 kb on - strandat 599.887 kb on - strandat 600.103 kb on + strandat 600.103 kb on + strandat 600.104 kb on - strandat 600.104 kb on - strandat 600.308 kb on + strand, within Rv0508at 600.308 kb on + strand, within Rv0508at 600.309 kb on - strand, within Rv0508at 600.309 kb on - strand, within Rv0508at 600.346 kb on - strand, within Rv0508at 600.376 kb on + strandat 600.384 kb on + strandat 600.402 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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599,124 + Rv0507 0.66 +0.3
599,125 - Rv0507 0.66 +0.0
599,392 - Rv0507 0.75 +0.2
599,403 - Rv0507 0.76 +0.4
599,434 + Rv0507 0.77 -0.9
599,434 + Rv0507 0.77 -0.2
599,776 - Rv0507 0.89 -0.3
599,871 + -0.2
599,872 - -0.3
599,872 - -1.0
599,887 - -0.3
600,103 + +0.5
600,103 + -0.8
600,104 - -1.6
600,104 - -0.2
600,308 + Rv0508 0.71 -0.0
600,308 + Rv0508 0.71 -0.3
600,309 - Rv0508 0.72 -1.7
600,309 - Rv0508 0.72 -0.7
600,346 - Rv0508 0.84 -0.3
600,376 + -0.6
600,384 + -0.2
600,402 + +0.3

Or see this region's nucleotide sequence