Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0391

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0389 and Rv0390 overlap by 4 nucleotidesRv0390 and Rv0391 overlap by 4 nucleotidesRv0391 and Rv0392c overlap by 4 nucleotides Rv0389: Rv0389 - Probable phosphoribosylglycinamide formyltransferase 2 PurT (GART 2) (gar transformylase 2) (5'-phosphoribosylglycinamide transformylase 2) (formate-dependent gar transformylase), at 468,335 to 469,594 Rv0389 Rv0390: Rv0390 - Conserved protein, at 469,591 to 470,013 Rv0390 Rv0391: Rv0391 - Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase), at 470,010 to 471,230 Rv0391 Rv0392c: Rv0392c - Probable membrane NADH dehydrogenase NdhA, at 471,227 to 472,639 Rv0392c Position (kb) 470 471 472Strain fitness (log2 ratio) -2 -1 0 1at 469.069 kb on + strand, within Rv0389at 469.070 kb on - strand, within Rv0389at 469.070 kb on - strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.235 kb on + strand, within Rv0389at 469.236 kb on - strand, within Rv0389at 469.597 kb on + strandat 469.598 kb on - strandat 469.608 kb on + strandat 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.738 kb on + strand, within Rv0390at 469.839 kb on + strand, within Rv0390at 469.916 kb on - strand, within Rv0390at 469.916 kb on - strand, within Rv0390at 470.130 kb on + strandat 470.146 kb on - strand, within Rv0391at 470.152 kb on - strand, within Rv0391at 470.202 kb on + strand, within Rv0391at 470.202 kb on + strand, within Rv0391at 470.203 kb on - strand, within Rv0391at 470.208 kb on + strand, within Rv0391at 470.208 kb on + strand, within Rv0391at 470.721 kb on + strand, within Rv0391at 470.929 kb on - strand, within Rv0391at 471.228 kb on + strandat 471.325 kb on - strandat 472.037 kb on - strand, within Rv0392c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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469,069 + Rv0389 0.58 +0.4
469,070 - Rv0389 0.58 -0.4
469,070 - Rv0389 0.58 -0.2
469,235 + Rv0389 0.71 +1.7
469,235 + Rv0389 0.71 -0.4
469,235 + Rv0389 0.71 -0.5
469,236 - Rv0389 0.72 +0.4
469,597 + -1.1
469,598 - -1.8
469,608 + +0.3
469,738 + Rv0390 0.35 -0.6
469,738 + Rv0390 0.35 -0.2
469,738 + Rv0390 0.35 -0.5
469,738 + Rv0390 0.35 -1.3
469,839 + Rv0390 0.59 -0.8
469,916 - Rv0390 0.77 -0.2
469,916 - Rv0390 0.77 -1.0
470,130 + -1.6
470,146 - Rv0391 0.11 -1.3
470,152 - Rv0391 0.12 +1.7
470,202 + Rv0391 0.16 -0.5
470,202 + Rv0391 0.16 -0.6
470,203 - Rv0391 0.16 -1.0
470,208 + Rv0391 0.16 -0.6
470,208 + Rv0391 0.16 -1.3
470,721 + Rv0391 0.58 -0.8
470,929 - Rv0391 0.75 -0.5
471,228 + +0.3
471,325 - -1.3
472,037 - Rv0392c 0.57 +0.2

Or see this region's nucleotide sequence