Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0177

Experiment: D-Lactate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0175 and Rv0176 overlap by 4 nucleotidesRv0176 and Rv0177 overlap by 4 nucleotidesRv0177 and Rv0178 overlap by 34 nucleotidesRv0178 and Rv0179c are separated by 30 nucleotides Rv0175: Rv0175 - Probable conserved Mce associated membrane protein, at 206,814 to 207,455 Rv0175 Rv0176: Rv0176 - Probable conserved Mce associated transmembrane protein, at 207,452 to 208,420 Rv0176 Rv0177: Rv0177 - Probable conserved Mce associated protein, at 208,417 to 208,971 Rv0177 Rv0178: Rv0178 - Probable conserved Mce associated membrane protein, at 208,938 to 209,672 Rv0178 Rv0179c: Rv0179c - Possible lipoprotein LprO, at 209,703 to 210,812 Rv0179c Position (kb) 208 209Strain fitness (log2 ratio) -2 -1 0 1at 207.420 kb on + strandat 207.422 kb on + strandat 207.423 kb on - strandat 207.423 kb on - strandat 208.010 kb on + strand, within Rv0176at 208.010 kb on + strand, within Rv0176at 208.092 kb on - strand, within Rv0176at 208.152 kb on - strand, within Rv0176at 208.208 kb on - strand, within Rv0176at 208.295 kb on - strand, within Rv0176at 208.295 kb on - strand, within Rv0176at 208.314 kb on - strand, within Rv0176at 208.315 kb on + strand, within Rv0176at 208.316 kb on - strand, within Rv0176at 208.726 kb on + strand, within Rv0177at 208.827 kb on + strand, within Rv0177at 208.828 kb on - strand, within Rv0177at 209.247 kb on + strand, within Rv0178at 209.460 kb on - strand, within Rv0178at 209.521 kb on - strand, within Rv0178at 209.574 kb on + strand, within Rv0178at 209.574 kb on + strand, within Rv0178at 209.574 kb on + strand, within Rv0178at 209.574 kb on + strand, within Rv0178at 209.574 kb on + strand, within Rv0178at 209.604 kb on + strandat 209.605 kb on - strandat 209.670 kb on + strandat 209.670 kb on + strandat 209.705 kb on - strandat 209.914 kb on + strand, within Rv0179cat 209.915 kb on - strand, within Rv0179cat 209.935 kb on + strand, within Rv0179cat 209.935 kb on + strand, within Rv0179cat 209.935 kb on + strand, within Rv0179cat 209.935 kb on + strand, within Rv0179cat 209.935 kb on + strand, within Rv0179cat 209.936 kb on - strand, within Rv0179cat 209.936 kb on - strand, within Rv0179cat 209.936 kb on - strand, within Rv0179cat 209.936 kb on - strand, within Rv0179cat 209.936 kb on - strand, within Rv0179c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Lactate 10 mM (C)
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207,420 + +0.4
207,422 + -0.4
207,423 - +1.3
207,423 - -1.4
208,010 + Rv0176 0.58 -0.3
208,010 + Rv0176 0.58 +0.4
208,092 - Rv0176 0.66 -0.8
208,152 - Rv0176 0.72 +0.0
208,208 - Rv0176 0.78 -0.0
208,295 - Rv0176 0.87 -0.9
208,295 - Rv0176 0.87 +0.1
208,314 - Rv0176 0.89 -0.6
208,315 + Rv0176 0.89 +0.1
208,316 - Rv0176 0.89 -0.2
208,726 + Rv0177 0.56 -0.6
208,827 + Rv0177 0.74 -0.0
208,828 - Rv0177 0.74 -1.9
209,247 + Rv0178 0.42 +0.2
209,460 - Rv0178 0.71 +0.7
209,521 - Rv0178 0.79 +0.2
209,574 + Rv0178 0.87 -0.4
209,574 + Rv0178 0.87 -0.5
209,574 + Rv0178 0.87 -1.1
209,574 + Rv0178 0.87 -1.1
209,574 + Rv0178 0.87 -0.3
209,604 + +0.5
209,605 - -1.4
209,670 + +0.3
209,670 + -0.0
209,705 - +0.1
209,914 + Rv0179c 0.19 -0.7
209,915 - Rv0179c 0.19 -0.5
209,935 + Rv0179c 0.21 +0.1
209,935 + Rv0179c 0.21 -1.1
209,935 + Rv0179c 0.21 -0.0
209,935 + Rv0179c 0.21 +0.5
209,935 + Rv0179c 0.21 +0.4
209,936 - Rv0179c 0.21 +0.1
209,936 - Rv0179c 0.21 +1.1
209,936 - Rv0179c 0.21 -0.3
209,936 - Rv0179c 0.21 -0.4
209,936 - Rv0179c 0.21 -1.1

Or see this region's nucleotide sequence