Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3300c

Experiment: 7H9 with Hygromycin B 0.0095 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3299c and Rv3300c are separated by 19 nucleotidesRv3300c and Rv3301c are separated by 11 nucleotidesRv3301c and Rv3302c are separated by 107 nucleotides Rv3299c: Rv3299c - Probable arylsulfatase AtsB (aryl-sulfate sulphohydrolase) (sulfatase), at 3,683,051 to 3,685,963 Rv3299c Rv3300c: Rv3300c - Conserved hypothetical protein, at 3,685,983 to 3,686,900 Rv3300c Rv3301c: Rv3301c - Probable phosphate-transport system transcriptional regulatory protein PhoU homolog 1 PhoY1, at 3,686,912 to 3,687,577 Rv3301c Rv3302c: Rv3302c - Probable glycerol-3-phosphate dehydrogenase GlpD2, at 3,687,685 to 3,689,442 Rv3302c Position (kb) 3685 3686 3687Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3685.976 kb on - strandat 3686.024 kb on + strandat 3686.399 kb on - strand, within Rv3300cat 3686.399 kb on - strand, within Rv3300cat 3686.437 kb on + strand, within Rv3300cat 3686.687 kb on - strand, within Rv3300cat 3686.687 kb on - strand, within Rv3300cat 3686.870 kb on + strandat 3687.094 kb on + strand, within Rv3301cat 3687.280 kb on + strand, within Rv3301cat 3687.443 kb on + strand, within Rv3301cat 3687.443 kb on + strand, within Rv3301cat 3687.444 kb on - strand, within Rv3301cat 3687.444 kb on - strand, within Rv3301cat 3687.565 kb on - strandat 3687.667 kb on - strandat 3687.667 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hygromycin B 0.0095 mM
remove
3,685,976 - -0.7
3,686,024 + +1.1
3,686,399 - Rv3300c 0.45 -3.2
3,686,399 - Rv3300c 0.45 -0.6
3,686,437 + Rv3300c 0.49 +1.8
3,686,687 - Rv3300c 0.77 -0.7
3,686,687 - Rv3300c 0.77 -0.3
3,686,870 + -0.5
3,687,094 + Rv3301c 0.27 +0.2
3,687,280 + Rv3301c 0.55 -0.6
3,687,443 + Rv3301c 0.80 -0.1
3,687,443 + Rv3301c 0.80 +0.2
3,687,444 - Rv3301c 0.80 -1.8
3,687,444 - Rv3301c 0.80 -0.2
3,687,565 - +0.0
3,687,667 - -0.2
3,687,667 - -1.2

Or see this region's nucleotide sequence