Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3079c

Experiment: 7H9 with Hygromycin B 0.0095 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3077 and Rv3078 are separated by 0 nucleotidesRv3078 and Rv3079c are separated by 15 nucleotidesRv3079c and Rv3080c are separated by 58 nucleotides Rv3077: Rv3077 - Possible hydrolase, at 3,439,541 to 3,441,352 Rv3077 Rv3078: Rv3078 - Probable hydroxylaminobenzene mutase Hab, at 3,441,353 to 3,441,754 Rv3078 Rv3079c: Rv3079c - Conserved protein, at 3,441,770 to 3,442,597 Rv3079c Rv3080c: Rv3080c - Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K), at 3,442,656 to 3,445,988 Rv3080c Position (kb) 3441 3442 3443Strain fitness (log2 ratio) -2 -1 0 1 2at 3441.028 kb on + strand, within Rv3077at 3441.140 kb on + strand, within Rv3077at 3441.171 kb on - strandat 3441.278 kb on + strandat 3441.279 kb on - strandat 3441.351 kb on - strandat 3441.366 kb on + strandat 3441.367 kb on - strandat 3441.367 kb on - strandat 3441.367 kb on - strandat 3441.367 kb on - strandat 3441.626 kb on - strand, within Rv3078at 3441.771 kb on + strandat 3441.772 kb on - strandat 3441.772 kb on - strandat 3441.811 kb on - strandat 3442.062 kb on + strand, within Rv3079cat 3442.062 kb on + strand, within Rv3079cat 3442.063 kb on - strand, within Rv3079cat 3442.104 kb on + strand, within Rv3079cat 3442.105 kb on - strand, within Rv3079cat 3442.125 kb on + strand, within Rv3079cat 3442.125 kb on + strand, within Rv3079cat 3442.125 kb on + strand, within Rv3079cat 3442.125 kb on + strand, within Rv3079cat 3442.125 kb on + strand, within Rv3079cat 3442.126 kb on - strand, within Rv3079cat 3442.362 kb on - strand, within Rv3079cat 3442.381 kb on + strand, within Rv3079cat 3442.483 kb on + strand, within Rv3079cat 3442.484 kb on - strand, within Rv3079cat 3442.782 kb on + strandat 3442.998 kb on + strand, within Rv3080cat 3443.198 kb on - strand, within Rv3080cat 3443.458 kb on + strand, within Rv3080cat 3443.460 kb on + strand, within Rv3080cat 3443.461 kb on - strand, within Rv3080c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hygromycin B 0.0095 mM
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3,441,028 + Rv3077 0.82 -0.6
3,441,140 + Rv3077 0.88 -1.3
3,441,171 - +1.8
3,441,278 + +0.0
3,441,279 - -1.6
3,441,351 - -0.5
3,441,366 + +0.7
3,441,367 - -0.1
3,441,367 - -1.0
3,441,367 - +0.8
3,441,367 - -0.4
3,441,626 - Rv3078 0.68 +0.5
3,441,771 + -0.0
3,441,772 - -1.0
3,441,772 - -0.2
3,441,811 - -0.8
3,442,062 + Rv3079c 0.35 -0.9
3,442,062 + Rv3079c 0.35 -1.3
3,442,063 - Rv3079c 0.35 -0.3
3,442,104 + Rv3079c 0.40 -0.2
3,442,105 - Rv3079c 0.40 -1.0
3,442,125 + Rv3079c 0.43 +0.1
3,442,125 + Rv3079c 0.43 -0.7
3,442,125 + Rv3079c 0.43 -0.7
3,442,125 + Rv3079c 0.43 -2.0
3,442,125 + Rv3079c 0.43 -0.5
3,442,126 - Rv3079c 0.43 -0.5
3,442,362 - Rv3079c 0.71 -0.2
3,442,381 + Rv3079c 0.74 -0.2
3,442,483 + Rv3079c 0.86 -0.7
3,442,484 - Rv3079c 0.86 +0.3
3,442,782 + -0.8
3,442,998 + Rv3080c 0.10 -0.2
3,443,198 - Rv3080c 0.16 +0.6
3,443,458 + Rv3080c 0.24 -1.4
3,443,460 + Rv3080c 0.24 -1.8
3,443,461 - Rv3080c 0.24 -1.7

Or see this region's nucleotide sequence