Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2924c

Experiment: 7H9 with Hygromycin B 0.0095 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2922c and Rv2922A are separated by 11 nucleotidesRv2922A and Rv2923c overlap by 14 nucleotidesRv2923c and Rv2924c are separated by 101 nucleotidesRv2924c and Rv2925c are separated by 358 nucleotides Rv2922c: Rv2922c - Probable chromosome partition protein Smc, at 3,234,189 to 3,237,806 Rv2922c Rv2922A: Rv2922A - Probable acylphosphatase AcyP (acylphosphate phosphohydrolase), at 3,237,818 to 3,238,099 Rv2922A Rv2923c: Rv2923c - Conserved protein, at 3,238,086 to 3,238,499 Rv2923c Rv2924c: Rv2924c - Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase), at 3,238,601 to 3,239,470 Rv2924c Rv2925c: Rv2925c - Probable ribonuclease III Rnc (RNase III), at 3,239,829 to 3,240,551 Rv2925c Position (kb) 3238 3239 3240Strain fitness (log2 ratio) -1 0 1 2at 3238.256 kb on - strand, within Rv2923cat 3238.399 kb on - strand, within Rv2923cat 3238.636 kb on - strandat 3238.655 kb on - strandat 3238.670 kb on + strandat 3238.670 kb on + strandat 3238.764 kb on + strand, within Rv2924cat 3238.765 kb on - strand, within Rv2924cat 3238.765 kb on - strand, within Rv2924cat 3238.857 kb on - strand, within Rv2924cat 3238.857 kb on - strand, within Rv2924cat 3238.914 kb on + strand, within Rv2924cat 3238.915 kb on - strand, within Rv2924cat 3239.252 kb on - strand, within Rv2924cat 3239.252 kb on - strand, within Rv2924cat 3239.266 kb on + strand, within Rv2924cat 3239.286 kb on + strand, within Rv2924cat 3239.286 kb on + strand, within Rv2924cat 3239.286 kb on + strand, within Rv2924cat 3239.287 kb on - strand, within Rv2924c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hygromycin B 0.0095 mM
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3,238,256 - Rv2923c 0.41 -0.3
3,238,399 - Rv2923c 0.76 +1.8
3,238,636 - -0.3
3,238,655 - -0.6
3,238,670 + -0.2
3,238,670 + +0.0
3,238,764 + Rv2924c 0.19 +0.1
3,238,765 - Rv2924c 0.19 +0.1
3,238,765 - Rv2924c 0.19 -0.3
3,238,857 - Rv2924c 0.29 -0.8
3,238,857 - Rv2924c 0.29 -0.1
3,238,914 + Rv2924c 0.36 -0.8
3,238,915 - Rv2924c 0.36 -0.6
3,239,252 - Rv2924c 0.75 -0.5
3,239,252 - Rv2924c 0.75 -0.4
3,239,266 + Rv2924c 0.76 -0.1
3,239,286 + Rv2924c 0.79 +0.5
3,239,286 + Rv2924c 0.79 -0.0
3,239,286 + Rv2924c 0.79 -1.0
3,239,287 - Rv2924c 0.79 -0.5

Or see this region's nucleotide sequence