Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0785

Experiment: 7H9 with Hygromycin B 0.0095 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0783c and Rv0784 are separated by 197 nucleotidesRv0784 and Rv0785 are separated by 15 nucleotidesRv0785 and Rv0786c are separated by 34 nucleotidesRv0786c and Rv0787 overlap by 6 nucleotides Rv0783c: Rv0783c - Possible multidrug resistance integral membrane efflux protein EmrB, at 876,818 to 878,440 Rv0783c Rv0784: Rv0784 - Conserved hypothetical protein, at 878,638 to 879,324 Rv0784 Rv0785: Rv0785 - Conserved protein, at 879,340 to 881,040 Rv0785 Rv0786c: Rv0786c - Conserved protein, at 881,075 to 881,464 Rv0786c Rv0787: Rv0787 - Unknown protein, at 881,459 to 882,418 Rv0787 Position (kb) 879 880 881 882Strain fitness (log2 ratio) -1 0 1at 878.560 kb on + strandat 878.836 kb on + strand, within Rv0784at 879.432 kb on - strandat 879.592 kb on - strand, within Rv0785at 879.653 kb on - strand, within Rv0785at 879.680 kb on - strand, within Rv0785at 879.680 kb on - strand, within Rv0785at 880.233 kb on + strand, within Rv0785at 880.233 kb on + strand, within Rv0785at 880.233 kb on + strand, within Rv0785at 880.234 kb on - strand, within Rv0785at 880.241 kb on - strand, within Rv0785at 880.683 kb on + strand, within Rv0785at 880.684 kb on - strand, within Rv0785at 880.732 kb on + strand, within Rv0785at 881.064 kb on + strandat 881.065 kb on - strandat 881.145 kb on + strand, within Rv0786cat 881.148 kb on + strand, within Rv0786cat 881.358 kb on + strand, within Rv0786cat 881.638 kb on + strand, within Rv0787at 881.812 kb on + strand, within Rv0787at 881.866 kb on + strand, within Rv0787

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hygromycin B 0.0095 mM
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878,560 + -0.1
878,836 + Rv0784 0.29 +1.2
879,432 - -0.4
879,592 - Rv0785 0.15 -0.7
879,653 - Rv0785 0.18 -0.1
879,680 - Rv0785 0.20 -0.4
879,680 - Rv0785 0.20 -0.1
880,233 + Rv0785 0.52 +0.1
880,233 + Rv0785 0.52 -0.0
880,233 + Rv0785 0.52 -0.5
880,234 - Rv0785 0.53 -0.1
880,241 - Rv0785 0.53 +0.1
880,683 + Rv0785 0.79 -0.9
880,684 - Rv0785 0.79 -0.9
880,732 + Rv0785 0.82 -0.5
881,064 + -0.6
881,065 - +0.8
881,145 + Rv0786c 0.18 +0.4
881,148 + Rv0786c 0.19 +0.0
881,358 + Rv0786c 0.73 +0.0
881,638 + Rv0787 0.19 -0.7
881,812 + Rv0787 0.37 -0.1
881,866 + Rv0787 0.42 -1.2

Or see this region's nucleotide sequence