Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0368c

Experiment: 7H9 with Hygromycin B 0.0095 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0366c and Rv0367c are separated by 28 nucleotidesRv0367c and Rv0368c are separated by 80 nucleotidesRv0368c and Rv0369c are separated by 5 nucleotidesRv0369c and Rv0370c are separated by 100 nucleotides Rv0366c: Rv0366c - Conserved hypothetical protein, at 444,222 to 444,815 Rv0366c Rv0367c: Rv0367c - Hypothetical protein, at 444,844 to 445,233 Rv0367c Rv0368c: Rv0368c - Conserved hypothetical protein, at 445,314 to 446,525 Rv0368c Rv0369c: Rv0369c - Possible membrane oxidoreductase, at 446,531 to 447,046 Rv0369c Rv0370c: Rv0370c - Possible oxidoreductase, at 447,147 to 448,043 Rv0370c Position (kb) 445 446 447Strain fitness (log2 ratio) -1 0 1 2at 444.522 kb on + strand, within Rv0366cat 444.522 kb on + strand, within Rv0366cat 444.522 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.661 kb on + strand, within Rv0366cat 444.985 kb on - strand, within Rv0367cat 445.263 kb on + strandat 445.391 kb on - strandat 445.566 kb on + strand, within Rv0368cat 445.622 kb on + strand, within Rv0368cat 445.646 kb on + strand, within Rv0368cat 445.647 kb on - strand, within Rv0368cat 445.662 kb on + strand, within Rv0368cat 445.662 kb on + strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.663 kb on - strand, within Rv0368cat 445.700 kb on + strand, within Rv0368cat 445.701 kb on - strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.786 kb on + strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.787 kb on - strand, within Rv0368cat 445.798 kb on + strand, within Rv0368cat 445.798 kb on + strand, within Rv0368cat 446.147 kb on + strand, within Rv0368cat 446.147 kb on + strand, within Rv0368cat 446.148 kb on - strand, within Rv0368cat 446.148 kb on - strand, within Rv0368cat 446.283 kb on + strand, within Rv0368cat 446.284 kb on - strand, within Rv0368cat 446.284 kb on - strand, within Rv0368cat 446.332 kb on - strand, within Rv0368cat 446.366 kb on - strand, within Rv0368cat 447.006 kb on + strandat 447.074 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hygromycin B 0.0095 mM
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444,522 + Rv0366c 0.51 -1.7
444,522 + Rv0366c 0.51 -0.4
444,522 + Rv0366c 0.51 +0.1
444,661 + Rv0366c 0.74 +0.1
444,661 + Rv0366c 0.74 -0.7
444,661 + Rv0366c 0.74 +0.4
444,985 - Rv0367c 0.36 -0.5
445,263 + -0.6
445,391 - -1.4
445,566 + Rv0368c 0.21 +0.7
445,622 + Rv0368c 0.25 +0.6
445,646 + Rv0368c 0.27 +0.7
445,647 - Rv0368c 0.27 +2.2
445,662 + Rv0368c 0.29 -0.5
445,662 + Rv0368c 0.29 +0.1
445,663 - Rv0368c 0.29 -0.9
445,663 - Rv0368c 0.29 +1.7
445,663 - Rv0368c 0.29 -0.0
445,663 - Rv0368c 0.29 -0.5
445,663 - Rv0368c 0.29 -1.1
445,663 - Rv0368c 0.29 -0.2
445,663 - Rv0368c 0.29 -0.1
445,700 + Rv0368c 0.32 +0.0
445,701 - Rv0368c 0.32 +0.3
445,786 + Rv0368c 0.39 -0.8
445,786 + Rv0368c 0.39 -0.2
445,786 + Rv0368c 0.39 -0.2
445,787 - Rv0368c 0.39 -1.4
445,787 - Rv0368c 0.39 +1.3
445,787 - Rv0368c 0.39 -0.4
445,798 + Rv0368c 0.40 +1.7
445,798 + Rv0368c 0.40 -0.5
446,147 + Rv0368c 0.69 +0.5
446,147 + Rv0368c 0.69 +0.1
446,148 - Rv0368c 0.69 +0.5
446,148 - Rv0368c 0.69 +0.2
446,283 + Rv0368c 0.80 -1.7
446,284 - Rv0368c 0.80 +0.4
446,284 - Rv0368c 0.80 -0.1
446,332 - Rv0368c 0.84 -0.1
446,366 - Rv0368c 0.87 -0.4
447,006 + -0.9
447,074 + -0.3

Or see this region's nucleotide sequence